Tibiofemoral Osteoarthritis After Surgical or Nonsurgical Treatment of Anterior Cruciate Ligament Rupture: A Systematic Review

Harris, Kyle P.; Driban, Jeffrey B.; Sitler, Michael R.; Cattano, Nicole M.; Balasubramanian, Easwaran; Hootman, Jennifer

doi:10.4085/1062-6050-49.3.89

Cited by 73 publications

(62 citation statements)

References 92 publications

(150 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Individuals with ACL injury are at high risk of poor longterm outcomes (eg, osteoarthritis, [18][19][20] knee pain, 21 diminished quality of life [21][22][23] ), and early symptoms predict more severe knee pain and symptoms 6 years after an ACL injury. 24 Furthermore, preoperative knee and body pain are important predictors of postsurgical outcomes 1 or 2 years after an ACL reconstruction.…”

mentioning

confidence: 99%

Posttraumatic Bone Marrow Lesion Volume and Knee Pain Within 4 Weeks After Anterior Cruciate Ligament Injury

Driban

Lohmander

Frobell

2017

Journal of Athletic Training

Self Cite

View full text Add to dashboard Cite

Context: After an anterior cruciate ligament (ACL) injury, a majority of patients have a traumatic bone marrow lesion (BML, or bone bruise). The clinical relevance of posttraumatic lesions remains unclear.Objective: To explore the cross-sectional associations between traumatic BML volume and self-reported knee pain and symptoms among individuals within 4 weeks of ACL injury.Design: Cross-sectional exploratory analysis of a randomized clinical trial.Setting: Orthopaedic departments at 2 hospitals in Sweden. Patients or Other Participants: As part of a randomized trial (knee anterior cruciate ligament nonoperative versus operative treatment [KANON] study), 121 young active adults (74% men, age ¼ 26 6 5 years, height ¼ 1.8 6 0.1 m, weight ¼ 76 6 13 kg) with an ACL tear were studied.Main Outcome Measure(s): The BML volume in the proximal tibia and distal femur was segmented using magnetic resonance images obtained within 4 weeks of injury. A radiologist evaluated the presence of depression fractures on the images. Pain and symptoms of the injured knee (Knee Injury and Osteoarthritis Outcome Score [KOOS] pain and symptoms subscales) were obtained the same day as imaging. We used linear regression models to assess the associations.Results: Most knees had at least 1 BML (96%), and the majority (57%) had a depression fracture. Whole-knee BML volume was not related to knee pain for the entire cohort (b ¼ À0.09, P ¼ .25). Among those without a depression fracture, larger whole-knee BML volume was associated with increased knee pain (b ¼ -0.46, P ¼ .02), whereas no association was found for those with a depression fracture (b ¼ 0.0, P ¼ .96). Larger medial (b ¼ -0.48, P ¼ .02) but not lateral (b ¼ -0.03, P ¼ .77) tibiofemoral BML volume was associated with greater pain. We found no association between BML volume and knee symptoms.Conclusions: We confirmed the absence of relationships between whole-knee BML volume and pain and symptoms within 4 weeks of ACL injury. Our findings extend previous reports in identifying weak associations between larger BML volume in the medial compartment and greater pain and between BML volume and greater pain among those without a depression fracture.Key Words: knee injuries, magnetic resonance imaging, sprains, trauma, patient-reported outcomes Key PointsWithin 4 weeks of anterior cruciate ligament injury, total-knee bone marrow lesion volume and self-reported pain and symptoms were not associated. More pain was weakly related to greater medial compartment and greater total-knee bone marrow lesion volume and to greater bone marrow lesion volume among participants without a depression fracture.

show abstract

mentioning

confidence: 99%

Posttraumatic Bone Marrow Lesion Volume and Knee Pain Within 4 Weeks After Anterior Cruciate Ligament Injury

Driban

Lohmander

Frobell

2017

Journal of Athletic Training

Self Cite

View full text Add to dashboard Cite

show abstract

“…Anterior cruciate ligament injury and reconstruction surgery (ACLR) dramatically increase the risk of developing knee osteoarthritis (OA), with 30-50% of patients developing OA within two decades (7,20). Though the causes of knee OA are poorly understood, a growing body of evidence implicates chronic quadriceps dysfunction as a critical contributor (2,9,29,34).…”

Section: Introductionmentioning

confidence: 99%

Quadriceps Function and Gait Kinetics after Anterior Cruciate Ligament Reconstruction

Blackburn

Pietrosimone

Harkey

et al. 2016

Medicine &Amp; Science in Sports &Amp; Exercise

View full text Add to dashboard Cite

show abstract

“…There may also be long-term consequences of ACL injury. Radiographic osteoarthritis (OA) may affect up to 71% of patients 10-15 years after their ACLR [158], and the prevalence of OA is similar, irrespective of whether patients have ACLR or not [81].…”

Section: Consequences Of Acl Injurymentioning

confidence: 99%

“…However, having surgical treatment does not automatically lead to satisfactory outcomes, and this may be related to expectations about RTS, knee stability, and ability to recover [213]. In the short term after ACLR, approximately 90% of patients achieved normal or nearly normal knee function regarding strength and stability [13], but in long-term studies a high incidence of OA has been reported [81,158].…”

Section: Outcome After Primary Aclrmentioning

confidence: 99%

One Anterior Cruciate Ligament injury is enough!: Focus on female football players

Fältström¹

View full text Add to dashboard Cite

Tibiofemoral Osteoarthritis After Surgical or Nonsurgical Treatment of Anterior Cruciate Ligament Rupture: A Systematic Review

Cited by 73 publications

References 92 publications

Posttraumatic Bone Marrow Lesion Volume and Knee Pain Within 4 Weeks After Anterior Cruciate Ligament Injury

Posttraumatic Bone Marrow Lesion Volume and Knee Pain Within 4 Weeks After Anterior Cruciate Ligament Injury

Quadriceps Function and Gait Kinetics after Anterior Cruciate Ligament Reconstruction

One Anterior Cruciate Ligament injury is enough!: Focus on female football players

Contact Info

Product

Resources

About