Thyroid FNA and benign thyroid disease

Poller, David; Yiangou, C.; Cummings, Michael H.; Boote, D.J.

doi:10.1016/s0140-6736(05)73824-1

Cited by 7 publications

(4 citation statements)

References 3 publications

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“…These false negative results are not surprising because the limitations of FNA in the setting of an MNG are well-known. 20,21 Of the 773 patients without a final diagnosis of thyroid cancer, 160 had the DLN removed. Table 1 shows the demographic distribution for patients with papillary and medul- lary thyroid cancer who had the DLN removed.…”

Section: Resultsmentioning

confidence: 99%

The Delphian Lymph Node in Thyroid Cancer

et al. 2008

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Although the clinical appearance of the DLN is not an accurate indicator of the presence of unsuspected thyroid cancer, metastatic involvement of the DLN is an adverse prognostic marker in papillary/medullary thyroid cancer. The presence of DLN metastasis in patients with thyroid cancer should alert the surgeon to the high probability of advanced disease and need for greater attention to the central and lateral lymph node compartments.

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Section: Resultsmentioning

confidence: 99%

The Delphian Lymph Node in Thyroid Cancer

et al. 2008

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“…If a nodule has been aspirated repeatedly and the repeat FNA contains mostly colloid and few follicular cells, then the term can be used ''suggestive of colloid nodule''). [35][36][37][38][39] See also Agenda Item ''Morphologic Criteria for Benign and Nonneoplastic Conditions'' and accompanying article in this issue by Pitman et al…”

Section: Diagnostic Terminology For Benign/nonneoplastic Conditionsmentioning

confidence: 99%

Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: A synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration State of the Science Conference

Baloch

LiVolsi

et al. 2008

Diagnostic Cytopathology

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The National Cancer Institute (NCI) sponsored the NCI Thyroid Fine-needle Aspiration (FNA) State of the Science Conference on October 22-23, 2007 in Bethesda, MD. The two-day meeting was accompanied by a permanent informational website and several on-line discussion periods between May 1 and December 15, 2007 (http://thyroidfna.cancer.gov). This document summarizes matters regarding diagnostic terminology/classification scheme for thyroid FNA interpretation and cytomorphologic criteria for the diagnosis of various benign and malignant thyroid lesions. (http://thyroidfna.cancer.gov/pages/info/agenda/).

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“…A significant number of patients are offered surgery for suspicious cytology on fine needle aspiration cytology (FNAC) which is considered the most reliable investigation in the diagnosis of malignant thyroid nodules preoperatively [1]. Although pathologists have formulated a scoring system for thyroid cytology, there are several drawbacks [2]. For instance, follicular carcinoma can only be confirmed by histological means, as capsular or vascular invasion are the criteria to determine malignancy.…”

Section: Introductionmentioning

confidence: 99%

A sonographic scoring system to assess the risk of thyroid malignancy

et al. 2016

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Prediction of thyroid malignancy with fine needle aspiration cytology or individual ultrasound characteristics has several limitations. This study evaluates the usefulness of a combination of ultrasound characteristics in predicting malignancy in patients with thyroid nodules. We assessed 189 thyroid nodules using ultrasonography and histology. Each nodule was assigned a score based on ultrasonographic characteristics. This score was compared with histology to identify ability to predict malignancy. There were 28 malignant nodules. The scoring system was appropriate for clinical use, obtaining an area under ROC curve of 0.822 [p< 0.0001] 95% confidence. FNAC of nodules with a score of more than 4 can be recommended (100% sensitivity). Nodules with a score less than 8 can be offered total thyroidectomy when FNAC is inconclusive (97.5% sensitivity). A combination of ultrasonographic criteria increase the accuracy of predicting malignancy in thyroid nodules.

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Thyroid FNA and benign thyroid disease

Cited by 7 publications

References 3 publications

The Delphian Lymph Node in Thyroid Cancer

The Delphian Lymph Node in Thyroid Cancer

Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: A synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration State of the Science Conference

A sonographic scoring system to assess the risk of thyroid malignancy

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