2014
DOI: 10.1590/0004-2730000002846
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Abstract: Objective: To establish whether there is a relationship between hyperprolactinemia and primary thyroid disorders, focusing on patients with autoimmune features. Materials and methods: The medical records of 100 patients with hyperprolactinemia (HPRL) were retrospectively examined. Records of thyroid ultrasonography (USG), basal serum levels of thyroid stimulating hormone, circulating free thyroxine, free triiodothyronine, antithyroglobulin (anti-Tg), and antithyroperoxidase (anti-TPO) antibodies were analyzed.… Show more

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Cited by 16 publications
(50 citation statements)
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References 24 publications
(50 reference statements)
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“…The frequency of nodular goiter was previously reported to be between 5 and 56% in Turkey [19, 21, 23, 26]. It was 30% in the present study and there was no significant difference between the CS patients and control subjects with respect to the frequency of nodular goiter (42.5% versus 30%, P > 0.05), which is not in agreement with earlier findings [1416].…”
Section: Discussioncontrasting
confidence: 82%
See 1 more Smart Citation
“…The frequency of nodular goiter was previously reported to be between 5 and 56% in Turkey [19, 21, 23, 26]. It was 30% in the present study and there was no significant difference between the CS patients and control subjects with respect to the frequency of nodular goiter (42.5% versus 30%, P > 0.05), which is not in agreement with earlier findings [1416].…”
Section: Discussioncontrasting
confidence: 82%
“…Thyroid autoantibodies were reported to be positive in 18–31% of the healthy population according to previous studies from Turkey which is a mild-to-moderate iodine deficient area [1924]. In the present study thyroid autoantibodies were detected in 15% of the controls.…”
Section: Discussionsupporting
confidence: 68%
“…Therefore, we searched for recent reports on screening studies of TgAb and TPOAb. To avoid the influence of diseases themselves, we only considered studies done on healthy control subjects in various regions in different countries [24][25][26][27][28][29][30][31][32][33][34][35][36][37]. In healthy subjects, the incidence of positive TgAb or TPOAb is …”
Section: Discussionmentioning
confidence: 99%
“…Although some case reports have shown interaction between macroprolactinemia and autoimmune thyroid disorders, other studies examining a large number of patients revealed no specific association. It has been shown that only a minority of patients with SLE had higher frequencies of macroprolactinemia [ 20 , 21 ]. The association of prolactin and macroprolactin with thyroid hormones and thyroid autoantibodies during pregnancy has not been studied before.…”
Section: Introductionmentioning
confidence: 99%