Thrombocytopenia Vs Pseudo thrombocytopenia Will indices help us???

Ps, Muthu Subramanian; E, Muthuvel; Chitra, S.; Sekar, Ganthimathy

doi:10.26452/ijrps.v11ispl2.2138

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…21 MPV and PDW both have a direct relationship and they usually change in the same direction. 22 The diag-nostic role of PDW in differentiating clonal and reactive thrombocytosis group is some what contra-dictory and was not found to be of any significance in our study.…”

Section: Discussioncontrasting

confidence: 55%

Platelet Indices as a Tool for Differentiation between Clonal Thrombocytosis and Reactive Thrombocytosis

Hafeez,

Nasir ud Din Khattak,

Naeem

et al. 2023

PAFMJ

View full text Add to dashboard Cite

Objective: To determine the efficacy of platelet indices as a tool for differentiation between clonal thrombocytosis and reactive thrombocytosis. Study Design: Cross sectional study. Place and Duration of Study: Department of Pathology, Combined Military Hospital, Lahore Pakistan, from Nov 2019 to Oct 2020. Methodology: Fifty-six subjects were included in Reactive thrombocytosis group and 56 in Clonal thrombocytosis group. Fresh blood in EDTA anticoagulant was analyzed to determine complete blood counts and platelet parameters (Platelet distribution width, mean platelet volume, Platelet large cell ratio, Plateletcrit) using the automated hematological analyzer Sysmex KX-21. Results: Mean age of the patients was 45.76 years with a range of 17-75 years. Assessing the cause of reactive thrombocytosi revealed that 20(35.7%) was infection and 16(28.5%) was iron deficiency anemia. In clonal thrombocytosis group 21(37.5%) were diagnosed with Chronic myeloid leukemia, 13(23.2%) with Essential thrombocythemia and 14(25%) with Polycythemia rubera vera. Platelet indices were compared in clonal thrombocytosis group and the reactive thrombocytosis group. Mean platelet volume, Platelet large cell ratio and Plateletcrit were significantly higher in the clonal thrombocytosis group (p=0.001). Difference in Platelet distribution width was not found to be statistically significant in the two groups (p=0.07) Conclusion: Platelet indices were higher in the clonal thrombocytosis group. Along with platelet count, they can serve as an efficient and cost-effective method in differentiating between clonal and reactive thrombocytosis.

show abstract

Section: Discussioncontrasting

confidence: 55%