Three-dimensional terahertz computed tomography of human bones

Bessou, Maryelle; Chassagne, Bruno; Caumes, Jean-Pascal; Pradère, Christophe; Maire, Philippe; Tondusson, Marc; Abraham, Emmanuel

doi:10.1364/ao.51.006738

Cited by 65 publications

(35 citation statements)

References 25 publications

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“…In addition to THz in vivo imaging, this modality has been expanded to many other medical fields. For instance, drug tracing within the skin [80], cartilage damage imaging [81], and skeletal computed tomography [82] have been performed. These trials have attracted intensive attention and support prospective application of this technique in clinical settings.…”

Section: Current Status Of Thz Imaging Studiesmentioning

confidence: 99%

Biomedical Applications of Terahertz Spectroscopy and Imaging

Xiang

Zhao

Yang

et al. 2016

Trends in Biotechnology

719

355

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Section: Current Status Of Thz Imaging Studiesmentioning

confidence: 99%

Biomedical Applications of Terahertz Spectroscopy and Imaging

Xiang

Zhao

Yang

et al. 2016

Trends in Biotechnology

719

355

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“…THz-TDS systems, which typically employ wide-band photoconductive antennas based on low-temperature-grown (LTG) III-V materials, are mainly applicable to spectroscopic applications that require a bandwidth of at least 3 THz [4], [5]. High-power RF devices, such as resonant-tunneling diodes, Gunn diodes, and vacuum devices, such as gyrotrons, are suitable for imaging applications [6], [7]. Photomixing methods have potential applications in thickness measurements, sensors, and hand-held systems requiring low power consumption and for which a moderate tuning range of ~1 THz is sufficient [8], [9].…”

Section: Introductionmentioning

confidence: 99%

SOA-Integrated Dual-Mode Laser and a PIN-Photodiode for Compact CW Terahertz System

Lee¹,

Kim²,

Han³

et al. 2016

ETRI J

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We designed and fabricated a semiconductor optical amplifier‐integrated dual‐mode laser (SOA‐DML) as a compact and widely tunable continuous‐wave terahertz (CW THz) beat source, and a pin‐photodiode (pin‐PD) integrated with a log‐periodic planar antenna as a CW THz emitter. The SOA‐DML chip consists of two distributed feedback lasers, a phase section for a tunable beat source, an amplifier, and a tapered spot‐size converter for high output power and fiber‐coupling efficiency. The SOA‐DML module exhibits an output power of more than 15 dBm and clear four‐wave mixing throughout the entire tuning range. Using integrated micro‐heaters, we were able to tune the optical beat frequency from 380 GHz to 1,120 GHz. In addition, the effect of benzocyclobutene polymer in the antenna design of a pin‐PD was considered. Furthermore, a dual active photodiode (PD) for high output power was designed, resulting in a 1.7‐fold increase in efficiency compared with a single active PD at 220 GHz. Finally, herein we successfully show the feasibility of the CW THz system by demonstrating THz frequency‐domain spectroscopy of an α‐lactose pellet using the modularized SOA‐DML and a PD emitter.

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“…X radiography also requires strict safety procedures, which are not needed when dealing with low intensity THz waves (0.4-12.4 meV photon energy within the 3-0.1 mm wavelength range) [11].…”

Section: A Potential Of Thz-tdi Scans As a Complementary Tool To X-rmentioning

confidence: 99%

Reflection terahertz time-domain imaging for analysis of an 18th century neoclassical easel painting

et al. 2015

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Terahertz time-domain imaging (THz-TDI) has been applied for imaging a hidden portrait and other subsurface composition layers of an 18th century (18C) easel painting by Nicolai Abildgaard, the most important 18C Danish neoclassical painter of historical and mythological subjects. For the first time, a real hidden portrait on an easel painting has been imaged by THz-TDI, with an unexpected richness of detail. THz C- and B-scans have been compared with images obtained by x-ray radiography and invasive cross-sectional imaging, leading to a deeper understanding of the strengths and limitations of this technique for art diagnostic purposes and defining its role among complementary tools for the investigation of art objects. We present a fast and effective method to separate single THz pulse reflections of interest from the entire signal across the image, adapted for uneven surfaces typically encountered in practical applications of the technique. Interfaces between layers of the painting have been successfully imaged, contributing substantially to the understanding of the structure of the painting.

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Three-dimensional terahertz computed tomography of human bones

Cited by 65 publications

References 25 publications

Biomedical Applications of Terahertz Spectroscopy and Imaging

Biomedical Applications of Terahertz Spectroscopy and Imaging

SOA-Integrated Dual-Mode Laser and a PIN-Photodiode for Compact CW Terahertz System

Reflection terahertz time-domain imaging for analysis of an 18th century neoclassical easel painting

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