Thirteen‐gene DNA methylation analysis of oral brushing samples: A potential surveillance tool for periodic monitoring of treated patients with oral cancer
Davide B. Gissi,
Roberto Rossi,
Jacopo Lenzi
et al.
Abstract:BackgroundWe evaluated the prognostic role of 13‐gene DNA methylation analysis by oral brushing repeatedly performed during the follow‐up of patients surgically treated for oral cancer.MethodsThis is a nested case–control study including 61 patients for a total of 64 outcomes (2/61 patients experienced multiple relapses). Samples were collected at baseline (4–10 months after OSCC resection) and repeatedly every 4–10 months until relapse or death. DNA methylation scores were classified as persistently positive,… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.