Third ventricular cavernous malformation: an unusual lesion

Abstract

Cavernomas constitute 5-10% of all the vascular malformations of the CNS. They commonly present during the 2nd and 5th decades of life. Intraventricular cavernomas constitute rare pathological entity, constituting 2.5-10.8% of cerebral cavernomas. (1) The natural history of intraventricular cavernomas remains undefined to some extent. Those in third ventricle are different in biological nature and need more aggressive therapy. These cavernomas appear to have the ability to grow very rapidly, resulting in significant morbidity. It is not known whether waiting after acute hemorrhage from an intraventricular cavernoma improves our ability to remove the lesion safely or if waiting unnecessarily increases the risk of hydrocephalus, additional bleeding, or further lesion growth.

A case of a cerebral cavernous malformation of the third ventricle that caused the syndrome of inappropriate secretion of antidiuretic hormone

“…[8] The common clinical symptoms are visual disturbance, memory disturbance, and increased signs of intracranial pressure, such as headache, nausea, vomiting, and consciousness disturbance. [689] Few cases of endocrine dysfunction caused by CCMs in the third ventricle have been reported, but they were unspecific. [689] In our case, endocrine examinations showed hyponatremia due to SIADH before surgery.…”

“…[3589] Complete resection of the CCMs is recommended because partial resection might result in regrowth or rebleeding. [35] In the literature, CCMs in the third ventricle were removed via the transcallosal, transcortical, or translamina terminalis approach by microsurgery, or via the transventricular approach by endoscopic surgery.…”

Intraventricular Cavernous Malformation: Review of the Literature and Report of Three Cases with Neuroendoscopic Resection

“…35 There has been debate around the timing of surgery, namely whether surgery should be performed directly after acute hemorrhage for decreasing the risk of hydrocephalus and preventing further bleeding, or delayed in order to facilitate the removal of the IVC. 38 Hydrocephalus was reported in 45% of the cases (59/131 patients), 52.5% of which (31/59 patients) had 3V cavernoma (3VCs). Epilepsy occurred in only 12.2% of cases (16/131 patients), which can be explained by a lack of perilesional gliosis as a epileptogenic area.…”

Third ventricular cavernoma: Report of two cases

“…[ 1 ] Third ventricular cavernomas are even rare, only 25 cases have been reported in the literature. [ 2 ] We report two more cases of third ventricular cavernomas.…”