Thin-layer chromatographic separation of methylene blue and related thiazine dyes

A Possible Phenomenon of Persistence in Pseudomonas aeruginosa Treated with Methylene Blue and Red Light

“…The results obtained using 6 μ m methylene blue are therefore compatible with the presence of persisters, but alternative interpretations cannot be disregarded. Since methylene blue is decomposed by light during irradiation , some susceptible cells could stochastically maintain their clonogenic ability until the inactivation of the photosensitizer. In addition, the selection of resistant mutants would produce survival curves similar to those obtained herein.…”

A Possible Phenomenon of Persistence in Pseudomonas aeruginosa Treated with Methylene Blue and Red Light

“…The results obtained using 6 μ m methylene blue are therefore compatible with the presence of persisters, but alternative interpretations cannot be disregarded. Since methylene blue is decomposed by light during irradiation , some susceptible cells could stochastically maintain their clonogenic ability until the inactivation of the photosensitizer. In addition, the selection of resistant mutants would produce survival curves similar to those obtained herein.…”

On the nature of Romanowsky dyes and the Romanowsky-Giemsa effect

“…Application of chromatographic separation procedures to Romanowsky stains (Taylor 1960, Loach 1971, Marshall & Lewis 1974a, 1974b, Marshall, Bentley & Lewis 1975, Marshall 1978 revealed the inadequacy of the traditional methods of organic chemistry as used in manufacturing processes to provide strictly pure forms of certain important dyes, the azures among them ; although solvent extraction with subsequent crystallization has proved valuable for purifying azure B from methylene blue (Marshall & Lewis 1976).…”

A Possible Phenomenon of Persistence in Pseudomonas aeruginosa Treated with Methylene Blue and Red Light

“…The results obtained using 6 μ m methylene blue are therefore compatible with the presence of persisters, but alternative interpretations cannot be disregarded. Since methylene blue is decomposed by light during irradiation , some susceptible cells could stochastically maintain their clonogenic ability until the inactivation of the photosensitizer. In addition, the selection of resistant mutants would produce survival curves similar to those obtained herein.…”

On the nature of Romanowsky dyes and the Romanowsky-Giemsa effect

“…Application of chromatographic separation procedures to Romanowsky stains (Taylor 1960, Loach 1971, Marshall & Lewis 1974a, 1974b, Marshall, Bentley & Lewis 1975, Marshall 1978 revealed the inadequacy of the traditional methods of organic chemistry as used in manufacturing processes to provide strictly pure forms of certain important dyes, the azures among them ; although solvent extraction with subsequent crystallization has proved valuable for purifying azure B from methylene blue (Marshall & Lewis 1976).…”

A Possible Phenomenon of Persistence in Pseudomonas aeruginosa Treated with Methylene Blue and Red Light

“…The results obtained using 6 μ m methylene blue are therefore compatible with the presence of persisters, but alternative interpretations cannot be disregarded. Since methylene blue is decomposed by light during irradiation , some susceptible cells could stochastically maintain their clonogenic ability until the inactivation of the photosensitizer. In addition, the selection of resistant mutants would produce survival curves similar to those obtained herein.…”

On the nature of Romanowsky dyes and the Romanowsky-Giemsa effect

“…Application of chromatographic separation procedures to Romanowsky stains (Taylor 1960, Loach 1971, Marshall & Lewis 1974a, 1974b, Marshall, Bentley & Lewis 1975, Marshall 1978 revealed the inadequacy of the traditional methods of organic chemistry as used in manufacturing processes to provide strictly pure forms of certain important dyes, the azures among them ; although solvent extraction with subsequent crystallization has proved valuable for purifying azure B from methylene blue (Marshall & Lewis 1976).…”