Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.11.030 View full text
Fatemeh S. Mirnaghi, Maria Rowena N. Monton, Janusz Pawliszyn

Abstract: A thin-film octadecyl (C18)-silica glass coating was developed as the extraction phase for an automated 96-blade solid-phase microextraction (SPME) system coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS). Various factors (e.g., sol-gel composition and aging time, coating preparation speed, coating thickness, and drying conditions) affecting the quality of C18-silica glass thin-film coating were studied and optimized. The results showed that the stability and durability of the coating are …

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