Thermotherapy for Retinoblastoma

Induction of apoptosis by carboplatin and hyperthermia alone or combined in WERI human retinoblastoma cells

“…This result was similar to the observation that CDDP increased p53 accumulation in retinoblastoma Y79 cells 22 . When cells were treated with hyperthermia, p53 accumulation increased at 24 h but it decreased to less than that in the unheated control cells at 48 and 72 h after heating (figure 4).…”

Induction of apoptosis by carboplatin and hyperthermia alone or combined in WERI human retinoblastoma cells

“…This result was similar to the observation that CDDP increased p53 accumulation in retinoblastoma Y79 cells 22 . When cells were treated with hyperthermia, p53 accumulation increased at 24 h but it decreased to less than that in the unheated control cells at 48 and 72 h after heating (figure 4).…”

Conservative treatment using laser diode and systemic chemotherapy for early‐stage bilateral retinoblastoma: A 14‐year prospective cohort study

“…The median longest diameter of all tumors in our study is comparable to that of other studies 12,13,26 . However, our median laser power was higher, while the median treatment duration was shorter than those in other studies worldwide 13,23,31 . This may be because we only included early‐stage tumors, while some authors selected tumors at all stages.…”

Treatment of small and medium retinoblastoma tumors with Iris diode laser

“…Several studies describe the efficacy of TTT as a primary treatment in small tumors with <1.5 DD. 7,11,12 In our study, not only smaller tumors, but also medium tumors of 1-6DD, as well as macular involving tumors, had favorable results with TTT with or without chemotherapy. Some benefits of TTT over external beam radiation or brachytherapy include more focal treatment with less risk of anterior segment complications and less destruction of surrounding normal retina.…”

“…Several studies describe the efficacy of TTT as a primary treatment in small tumors with <1.5 DD. 7,11,12 In our study, not only smaller tumors, (Nd:YAG) lasers. The authors reported settings but did not describe differences in outcomes between groups.…”

Induction of apoptosis by carboplatin and hyperthermia alone or combined in WERI human retinoblastoma cells

“…This result was similar to the observation that CDDP increased p53 accumulation in retinoblastoma Y79 cells 22 . When cells were treated with hyperthermia, p53 accumulation increased at 24 h but it decreased to less than that in the unheated control cells at 48 and 72 h after heating (figure 4).…”

Conservative treatment using laser diode and systemic chemotherapy for early‐stage bilateral retinoblastoma: A 14‐year prospective cohort study

“…The median longest diameter of all tumors in our study is comparable to that of other studies 12,13,26 . However, our median laser power was higher, while the median treatment duration was shorter than those in other studies worldwide 13,23,31 . This may be because we only included early‐stage tumors, while some authors selected tumors at all stages.…”

Treatment of small and medium retinoblastoma tumors with Iris diode laser

“…Several studies describe the efficacy of TTT as a primary treatment in small tumors with <1.5 DD. 7,11,12 In our study, not only smaller tumors, but also medium tumors of 1-6DD, as well as macular involving tumors, had favorable results with TTT with or without chemotherapy. Some benefits of TTT over external beam radiation or brachytherapy include more focal treatment with less risk of anterior segment complications and less destruction of surrounding normal retina.…”

“…Several studies describe the efficacy of TTT as a primary treatment in small tumors with <1.5 DD. 7,11,12 In our study, not only smaller tumors, (Nd:YAG) lasers. The authors reported settings but did not describe differences in outcomes between groups.…”

Induction of apoptosis by carboplatin and hyperthermia alone or combined in WERI human retinoblastoma cells

“…This result was similar to the observation that CDDP increased p53 accumulation in retinoblastoma Y79 cells 22 . When cells were treated with hyperthermia, p53 accumulation increased at 24 h but it decreased to less than that in the unheated control cells at 48 and 72 h after heating (figure 4).…”

Conservative treatment using laser diode and systemic chemotherapy for early‐stage bilateral retinoblastoma: A 14‐year prospective cohort study

“…The median longest diameter of all tumors in our study is comparable to that of other studies 12,13,26 . However, our median laser power was higher, while the median treatment duration was shorter than those in other studies worldwide 13,23,31 . This may be because we only included early‐stage tumors, while some authors selected tumors at all stages.…”

Treatment of small and medium retinoblastoma tumors with Iris diode laser

“…Several studies describe the efficacy of TTT as a primary treatment in small tumors with <1.5 DD. 7,11,12 In our study, not only smaller tumors, but also medium tumors of 1-6DD, as well as macular involving tumors, had favorable results with TTT with or without chemotherapy. Some benefits of TTT over external beam radiation or brachytherapy include more focal treatment with less risk of anterior segment complications and less destruction of surrounding normal retina.…”

“…Several studies describe the efficacy of TTT as a primary treatment in small tumors with <1.5 DD. 7,11,12 In our study, not only smaller tumors, (Nd:YAG) lasers. The authors reported settings but did not describe differences in outcomes between groups.…”