Thermoregulatory Sweat Testing in Patients With Erythromelalgia

Davis, Mark D.P.; Genebriera, Joseph; Sandroni, Paola; Fealey, Robert D.

doi:10.1001/archderm.142.12.1583

Cited by 33 publications

(31 citation statements)

References 20 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11,12 Neurophysiologic assessment in the majority of patients demonstrated decreased sweating indicative of a small-fiber neuropathy on quantitative sudomotor axon reflex test and thermoregulatory sweat testing, as previously described in adults. [11][12][13] The large-fiber neuropathy determined by electromyographic and nerve conduction studies in adult patients was not found.…”

Section: Discussionmentioning

confidence: 99%

“…13 Serologic testing: the paraneoplastic autoantibody comprehensive panel Tests for antineuronal nuclear antibodies type 1 (sometimes called anti-Hu) and type 2 (or anti-Ri), amphiphysin antibody, Purkinje cell cytoplasmic antibody (PCA) type 1 (sometimes called anti-Yo), PCA type 2, PCA-Tr, and collapsin response-mediator protein antibody were done as a one-step indirect immunofluorescence screening assay. 14 antibodies of P/Q-type and N-type specificities were immunoprecipitation assays.…”

Section: Neurophysiologic and Vascular Testingmentioning

confidence: 99%

See 1 more Smart Citation

Pediatric erythromelalgia: A?retrospective review of 32 cases evaluated at Mayo Clinic over a 37-year period

Cook-Norris

Tollefson

Cruz-Inigo

et al. 2012

Journal of the American Academy of Dermatology

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Neurophysiologic and Vascular Testingmentioning

confidence: 99%

Pediatric erythromelalgia: A?retrospective review of 32 cases evaluated at Mayo Clinic over a 37-year period

Cook-Norris

Tollefson

Cruz-Inigo

et al. 2012

Journal of the American Academy of Dermatology

Self Cite

View full text Add to dashboard Cite

“…The symptoms most commonly affect the feet and legs bilaterally but can affect hands and even the face [5]. The condition is also associated with anhidrosis [6]. Erythromelalgia has been documented in the literature for almost 150 years, but its prevalence, aetiology, and pathogenesis remain elusive.…”

Section: Introductionmentioning

confidence: 99%

Erythromelalgia? A Clinical Study of People Who Experience Red, Hot, Painful Feet in the Community

Friberg

Chen

Tarr

et al. 2013

International Journal of Vascular Medicine

View full text Add to dashboard Cite

We recruited a population of people who clinically suffer from the symptoms of erythromelalgia, red, hot, painful feet made worse by heat and improved by cooling, to better characterise this population and measure their quality of life (QOL). Ninety-two individuals completed the QOL surveys, and 56 individuals were clinically assessed. There was a 3 : 1 ratio of females to males with an average age of 61 years. The estimated prevalence of people who had clinical symptoms of erythromelalgia in the Dunedin community was 15/100,000. Only 27% of people had received a diagnosis for their symptoms despite seeking medical attention. People in the study population had worse quality of life than the general New Zealand population (P < 0.001). In the majority of participants symptoms had a mild-moderate effect on their quality of life. The results of this study indicate that the number of people who have clinical symptoms of erythromelalgia is much greater than is commonly accepted and that the majority of these individuals go unrecognised by the medical profession despite seeking help. They have significantly diminished QOL with the majority of people having mild-to-moderate symptoms.

show abstract

“…Some adrenergic abnormalities were detected in patients with erythermalgia 5,7 . Erythermalgia is due to a small‐fibre neuropathy 8 involving C‐fibres, as shown by microneurography 8 sympathetic skin response test 5 and thermoregulatory sweat testing 9 …”

mentioning

confidence: 99%