2010
DOI: 10.1063/1.3496359
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Thermal mixing of two miscible fluids in a T-shaped microchannel

Abstract: In this paper, thermal mixing characteristics of two miscible fluids in a T-shaped microchannel are investigated theoretically, experimentally, and numerically. Thermal mixing processes in a T-shaped microchannel are divided into two zones, consisting of a T-junction and a mixing channel. An analytical two-dimensional model was first built to describe the heat transfer processes in the mixing channel.In the experiments, de-ionized water was employed as the working fluid. Laser induced fluorescence method was u… Show more

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Cited by 63 publications
(30 citation statements)
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“…An important requirement for these systems is the ability to rapidly and efficiently mix small amounts of samples at microscales 15,66 . Various techniques have been utilized to enable rapid mixing in microfluidic devices including chaotic advection 13,14,26,33,40,62 , hydrodynamic focusing 45,51 , electrokinetically driven mixing 16,23,32,48,60 , 3D combinatorial bubble-based mixing 38,47 , and thermally- 63,69 as well as optically-induced 25 mixing. Recently, acoustic-based mixers 39,43,52,59,64 have generated significant interest because of their non-invasive nature.…”
Section: Introductionmentioning
confidence: 99%
“…An important requirement for these systems is the ability to rapidly and efficiently mix small amounts of samples at microscales 15,66 . Various techniques have been utilized to enable rapid mixing in microfluidic devices including chaotic advection 13,14,26,33,40,62 , hydrodynamic focusing 45,51 , electrokinetically driven mixing 16,23,32,48,60 , 3D combinatorial bubble-based mixing 38,47 , and thermally- 63,69 as well as optically-induced 25 mixing. Recently, acoustic-based mixers 39,43,52,59,64 have generated significant interest because of their non-invasive nature.…”
Section: Introductionmentioning
confidence: 99%
“…5C-E. The difference in size distribution could due to the fact that higher concentration of glucose (pumped by Pump 2) resulted in a higher reaction rate that consequently increased the supersaturation, 20 higher supersaturation normally results in smaller primary particles and the presence of PVP prevents aggregation. [32] In addition to using multiple micropumps for driving liquids in parallel, we also demonstrated pumping liquids in series using cascaded pump configurations, as shown in Supporting Information S5.…”
Section: A Modular Microfluidic Platform Enabled By the Mre Microactumentioning
confidence: 99%
“…[17] A passive approach for obtaining mixing is to induce secondary flows by altering the structures or geometries of the flow channels. [18] On the other hand, active mixing can be achieved using acoustic, [19] thermal, [20] CEW, [21] and electrokinetic [22] effects. Similar to the problems associated with micropumps, current micromixers often require bulky peripherals to drive them, or have limited liquids that can be mixed.…”
Section: Introductionmentioning
confidence: 99%
“…Xu et al. analyzed mixing of two solutions, one heated and one cold, in a T‐shaped micro‐mixer. Using temperature‐dependent fluorescence of Rhodamine B, two heat transfer zones could be differentiated.…”
Section: Mixingmentioning
confidence: 99%
“…In one example a PCR microfluidic chamber designed by Kim et al [45], involved alternating heating of two channel segments to enhance mixing. Xu et al [46] analyzed mixing of two solutions, one heated and one cold, in a T-shaped micro-mixer. Using temperaturedependent fluorescence of Rhodamine B, two heat transfer zones could be differentiated.…”
Section: Active Mixersmentioning
confidence: 99%