Therapeutic response of West African Dwarf goats infected with Peste des Petits Ruminants whose oral lesions were treated with oxytetracycline long acting and gentian violet topical spray

Ugochukwu, Iniobong Chukwuebuka Ikenna; Ugochukwu, Emmanuel Ikenna; Chukwu, C. C.

doi:10.12980/apjtd.7.2017d7-234

Cited by 2 publications

(2 citation statements)

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“…Narayanan et al (2008), treated clinical cases of PPR were treated with broad-spectrum antibiotics. The findings of this present study supports the argument that incorporation of oxytetracycline into the treatment regime of PPR can be effective in combating secondary bacterial infection in PPR infection (Ugochukwu et al, 2017a).…”

Section: Discussionsupporting

confidence: 87%

The Clinicopathological Evaluations of the Efficacy of Incorporation of Amantadine Hydrochloride in the Treatment of West African Dwarf Goats Experimentally Infected with Peste des Petits Ruminants Virus

et al. 2019

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Peste des petits ruminants poses a major threat to the development of small ruminant production. The objective of this study was to determine the comparative efficacy of amantadine hydrochloride (HCl), oxytetracycline long acting (LA) and levamisole in West African dwarf (WAD) goats experimentally infected with PPR. In addition to the presence of the characteristic clinical signs, complement ELISA and haem agglutination inhibition (HI) tests were used to confirm PPR infection in the West African dwarf goats, then treatment was instituted in the different groups namely, group 1 which was treated with amantadine HCl orally, oxytetracycline LA intramuscularly (IM) and levamisole per os. Group 2 was treated with oxytetracycline LA IM and levamisole. Group 3 was treated with levamisole while group 4 served as untreated control. The physiological parameters namely rectal temperature, pulse rate and respiratory rates of the different groups were recorded. The mortality rates in the different treatment groups were also recorded. The respiratory rates of the WAD goats increased as the infection progressed, but the increase was not significant (P>0.05). The treatment helped reduce the respiratory rates in the treated WAD. The rectal temperatures of all the animals in the different treatment groups increased only slightly as the infection progressed and was not significant (P>0.05). The percentage mortalities were 0% in Group 1, 25% in the Group 2, 50% in the treated group 3 and highest (75%) in the untreated group respectively. In conclusion, incorporation of specific antiviral agents like amantadine hydrochloride in the treatment regimen with oxytetracycline and levamisole particularly during the early stages of the infection can reduce morbidity and mortality of the disease to the barest minimum.

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Section: Discussionsupporting

confidence: 87%

The Clinicopathological Evaluations of the Efficacy of Incorporation of Amantadine Hydrochloride in the Treatment of West African Dwarf Goats Experimentally Infected with Peste des Petits Ruminants Virus

et al. 2019

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“…Out of 42 goats, 38 (93.23%) recovered after receiving an antibiotic and anti-inflammatory protocol of ampicillin trihydrate, colistin sulfate, and dexamethasone acetate IM once daily for 3 days, and metronidazole 500 mg/35 kg body weight orally three times daily for 3 days ( 42 ). Long-acting tetracyclines and topical gentian violet helped resolve the PPR lesions within 3 weeks ( 43 ). The antiparasitic endectocide ivermectin inhibited PPRV replication in vitro , suggesting that it might be used as a repurposed antiviral drug against PPRV ( 44 ).…”

Section: Peste Des Petits Ruminantmentioning

confidence: 99%

Camel viral diseases: Current diagnostic, therapeutic, and preventive strategies

Kandeel

Al-Mubarak

2022

Front. Vet. Sci.

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Many pathogenic viruses infect camels, generally regarded as especially hardy livestock because of their ability to thrive in harsh and arid conditions. Transmission of these viruses has been facilitated by the commercialization of camel milk and meat and their byproducts, and vaccines are needed to prevent viruses from spreading. There is a paucity of information on the effectiveness of viral immunizations in camels, even though numerous studies have looked into the topic. More research is needed to create effective vaccines and treatments for camels. Because Camels are carriers of coronavirus, capable of producing a powerful immune response to recurrent coronavirus infections. As a result, camels may be a suitable model for viral vaccine trials since vaccines are simple to create and can prevent viral infection transfer from animals to humans. In this review, we present available data on the diagnostic, therapeutic, and preventative strategies for the following viral diseases in camels, most of which result in significant economic loss: camelpox, Rift Valley fever, peste des petits ruminants, bovine viral diarrhea, bluetongue, rotavirus, Middle East respiratory syndrome, and COVID-19. Although suitable vaccines have been developed for controlling viral infections and perhaps interrupting the transmission of the virus from the affected animals to blood-feeding vectors, there is a paucity of information on the effectiveness of viral immunizations in camels and more research is needed. Recent therapeutic trials that include specific antivirals or supportive care have helped manage viral infections.

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Therapeutic response of West African Dwarf goats infected with Peste des Petits Ruminants whose oral lesions were treated with oxytetracycline long acting and gentian violet topical spray

Cited by 2 publications

References 16 publications

The Clinicopathological Evaluations of the Efficacy of Incorporation of Amantadine Hydrochloride in the Treatment of West African Dwarf Goats Experimentally Infected with Peste des Petits Ruminants Virus

The Clinicopathological Evaluations of the Efficacy of Incorporation of Amantadine Hydrochloride in the Treatment of West African Dwarf Goats Experimentally Infected with Peste des Petits Ruminants Virus

Camel viral diseases: Current diagnostic, therapeutic, and preventive strategies

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