Therapeutic potential of fucoidan in dentistry: A review

Abstract

Fucoidan, produced by the cell walls of brown seaweed, possesses biological effects, covering anticancer, antiviral, anti-inflammatory, antioxidant, and a potential for promoting angiogenesis and osteogenesis. This study aimed to compile diverse scientific results on fucoidan’s therapeutic prospect in dentistry and the mechanism of action in the therapy of oral diseases. A literature search was carried out using keywords with Boolean operators, including fucoidan (AND) oral (OR) dental (OR) dentistry, to identify related publications from PubMed, ScienceDirect, and Google Scholar databases. The results showed that fucoidan had various therapeutic potentials in the field of dentistry, including anticancer, anti-inflammatory, radioprotection, protection of dental pulp tissue, and bone regeneration. These characteristics were related to the sulfate composition and molecular weight. Fucoidan has various therapeutic potentials crucial for oral health. Hence, it might be used for material development and drug production in dentistry