Therapeutic drug monitoring of vancomycin in the case of augmented renal clearance: a case report of a paediatric patient
Hasan Memiş,
Ahmet Çakır,
Ayşe Ülgey
Abstract:Augmented renal clearance (ARC) is a condition in which renal circulation increases, causing drug levels in the blood to remain at subtherapeutic levels in severe trauma patients. Vancomycin, a hydrophilic anti-Gram-positive drug, has been shown in the literature to have its levels fall below the therapeutic range in the case of ARC. However, vancomycin dosing recommendations in the case of ARC are still lacking. Here, we identify an ARC case measured with urinary creatinine clearance in a severe trauma paedia… Show more
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