Therapeutic Drug Monitoring of Antiretroviral Drugs in the Management of Human Immunodeficiency Virus Infection

Rakhmanina, Natella; Porte, C.J.L. la

doi:10.1016/b978-0-12-385467-4.00017-8

Cited by 3 publications

(2 citation statements)

References 146 publications

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“…ART can effectively control the virus if administered consistently and correctly, allowing individuals to lead healthy lives. Preexposure prophylaxis (PrEP) is a preventive approach that involves regularly taking medication to decrease the risk of contracting HIV [31].…”

Section: Human Immunode Ciency Virus (Hiv)mentioning

confidence: 99%

Mpox, STIs, and HIV in the LGBTQIA2S+ Community: What can be learned from bibliometric analysis?

Adnyana

2023

Preprint

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The LGBTQIA2S + community is vulnerable to health problems, including triple-burden diseases such as Mpox, sexually transmitted infections (STIs), and HIV positivity. This zoonotic disease is a global health burden in nonendemic countries. With increasing cases of the three diseases, this community faces various threats, obstacles, and challenges. This review aimed to identify the threats and barriers to triple-burden disease, including mpox infection, STIs, and HIV infection, simultaneously in LGBTQIA2S + populations. A bibliometric study approach was used to map these three diseases' research journeys and findings worldwide. The LGBTQIA2S + community faced distinct health disparities, including the triple disease burden, which refers to the higher prevalence and impact of multiple health conditions in this group. Although there has been no specific research on the triple burden of Mpox, STIs, and HIV in the LGBTQIA2S + community, this population faces various direct and indirect threats and barriers. These include stigma, discrimination, a lack of culturally competent care, limited resource access, and mental health effects. A comprehensive approach that includes destigmatization efforts, education, accessible healthcare services, and mental health support is necessary to address these challenges and improve the LGBTQIA2S + community's overall health outcomes. Promoting inclusivity, understanding, and awareness is essential to reduce community barriers and improve health.

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Section: Human Immunode Ciency Virus (Hiv)mentioning

confidence: 99%

Mpox, STIs, and HIV in the LGBTQIA2S+ Community: What can be learned from bibliometric analysis?

Adnyana

2023

Preprint

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“…The d4T/ddI combination is associated with high toxicity and hence it is not often recommended [ 148 ]. The most popular NRTIs are cytidine analogs (XTC), FTC, 3TC, and TDF, which form part of the first-line therapy [ 149 , 150 , 151 , 152 , 153 ]. FTC and 3TC are similar in chemical structures with different pharmacokinetic and pharmacodynamic properties, and they have required deoxynucleosides for HIV DNA synthesis.…”

Section: Common Highly Active Antiretroviral Therapy (Haart) Combinat...mentioning

confidence: 99%

The Potential of Spirulina platensis to Ameliorate the Adverse Effects of Highly Active Antiretroviral Therapy (HAART)

2022

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The human immunodeficiency virus (HIV) is one of the most prevalent diseases globally. It is estimated that 37.7 million people are infected with HIV globally, and 8.2 million persons are infected with the virus in South Africa. The highly active antiretroviral therapy (HAART) involves combining various types of antiretroviral drugs that are dependent on the infected person’s viral load. HAART helps regulate the viral load and prevents its associated symptoms from progressing into acquired immune deficiency syndrome (AIDS). Despite its success in prolonging HIV-infected patients’ lifespans, the use of HAART promotes metabolic syndrome (MetS) through an inflammatory pathway, excess production of reactive oxygen species (ROS), and mitochondrial dysfunction. Interestingly, Spirulina platensis (SP), a blue-green microalgae commonly used as a traditional food by Mexican and African people, has been demonstrated to mitigate MetS by regulating oxidative and inflammatory pathways. SP is also a potent antioxidant that has been shown to exhibit immunological, anticancer, anti-inflammatory, anti-aging, antidiabetic, antibacterial, and antiviral properties. This review is aimed at highlighting the biochemical mechanism of SP with a focus on studies linking SP to the inhibition of HIV, inflammation, and oxidative stress. Further, we propose SP as a potential supplement for HIV-infected persons on lifelong HAART.

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Therapeutic Drug Monitoring of Antiretrovirals

Marzinke

2016

Clinical Challenges in Therapeutic Drug Monitoring

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Therapeutic Drug Monitoring of Antiretroviral Drugs in the Management of Human Immunodeficiency Virus Infection

Cited by 3 publications

References 146 publications

Mpox, STIs, and HIV in the LGBTQIA2S+ Community: What can be learned from bibliometric analysis?

Mpox, STIs, and HIV in the LGBTQIA2S+ Community: What can be learned from bibliometric analysis?

The Potential of Spirulina platensis to Ameliorate the Adverse Effects of Highly Active Antiretroviral Therapy (HAART)

Therapeutic Drug Monitoring of Antiretrovirals

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