2006
DOI: 10.1016/j.neuron.2006.01.018
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: The molecular mechanisms that regulate the production and diversity of olfactory bulb interneurons remain poorly understood. With the exception of the GABAergic/dopaminergic subtype in the glomerular layer, no information exists concerning the generation of the other subtypes. Here we show that the recently identified zinc finger transcription factor Sp8 is expressed in neurogenic regions, which give rise to olfactory bulb interneurons at embryonic and postnatal time points and remains expressed in the calreti… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

30
325
4
3

Year Published

2006
2006
2015
2015

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 220 publications
(362 citation statements)
references
References 40 publications
30
325
4
3
Order By: Relevance
“…In contrast, the production of CR-and TH-expressing PG cells follows an opposite trend with a progressive increase with age (De Marchis et al 2007 ). According to previous studies (Hack et al 2005 ;Kohwi et al 2005 ;Waclaw et al 2006 ) this work suggests that the population of SVZ progenitors with a PG fate is composed of a heterogeneous pool of neurochemically specified elements, and indicates that the relative contribution of these different subsets changes with time. Therefore, neurogenesis in the OB does not reflect a simple turnover of the whole interneuron population of the GL, but it may serve to finely modulate the relative amounts of distinct OB interneuron subpopulations.…”
Section: Temporal Differences In the Generation Of Ob Interneuron Subsupporting
confidence: 56%
See 4 more Smart Citations
“…In contrast, the production of CR-and TH-expressing PG cells follows an opposite trend with a progressive increase with age (De Marchis et al 2007 ). According to previous studies (Hack et al 2005 ;Kohwi et al 2005 ;Waclaw et al 2006 ) this work suggests that the population of SVZ progenitors with a PG fate is composed of a heterogeneous pool of neurochemically specified elements, and indicates that the relative contribution of these different subsets changes with time. Therefore, neurogenesis in the OB does not reflect a simple turnover of the whole interneuron population of the GL, but it may serve to finely modulate the relative amounts of distinct OB interneuron subpopulations.…”
Section: Temporal Differences In the Generation Of Ob Interneuron Subsupporting
confidence: 56%
“…The local cues are insufficient to reprogram the migratory fate of MGE precursors whereas LGE cells selectively migrate along the pathway to the OB. This potential is very similar to that of the postnatal and adult SVZ (Lois and Alvarez-Buylla 1994 ; Luskinexpression is not restricted to the embryonic phase of development, but has been detected in cells of the postnatal/adult SVZ, as well as in the RMS and in the GCL and GL of the OB, suggesting that a regional specification of neuronal subtypes might also apply to adult neurogenesis (Stenman et al 2003 ;Waclaw et al 2006 ).…”
Section: Spatial Specification Of Lge Progenitorsmentioning
confidence: 59%
See 3 more Smart Citations