The VALUE National Hysterectomy Study: Description of the Patients and Their Surgery

“…The CREST study on the complication rate for minor and major operations, reports a 25% complication rate for vaginal hysterectomy and a 43% for abdominal hysterectomy [76]. The VALUE study confirmed that more than 10% of women treated by hysterectomy for DUB reported immediate or long-term complications [77]. These complication rates are significantly higher than those of firstgeneration endometrial ablation techniques.…”

Section: Hysterectomymentioning

confidence: 93%

Treatment options for dysfunctional uterine bleeding: evaluation of clinical results

et al. 2011

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Abnormal uterine bleeding is one of the most common problems in women of reproductive age, and dysfunctional uterine bleeding (DUB) accounts for about half the cases. The aim of this review is to present all treatment options for women suffering from DUB and to evaluate their effectiveness. A detailed search strategy on electronic databases was carried out to identify trials and reviews on management of abnormal uterine bleeding. Tranexamic acid is the most effective medical treatment. A levonorgestrel-releasing intrauterine device is a low-cost, simple, and effective medical method, comparable to hysterectomy in terms of quality of life. In cases of DUB resistant to medical treatment, surgical treatment should be offered. First-generation ablation techniques are effective, but have a long learning curve. Second-generation ablation devices are highly effective and safe alternatives, thoroughly compared to first-generation techniques. Hysterectomy is the only method that guarantees treatment of dysfunctional uterine bleeding, but is a major operation associated with higher morbidity and mortality rates. Proper counseling of each woman with DUB regarding all treatment modalities can provide the best choice for each patient. More prospective randomized trials are needed to establish the effectiveness of these methods

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“…However, it is associated with an overall 3.5% operative and 9% postoperative complication rates and a mortality rate of 0.38 per 1000. 51 Long-term risks include early ovarian failure, pelvic pain, sexual dysfunction and urinary problems.…”

Section: Surgical Treatmentmentioning

confidence: 99%

Gynaecological problems and choices for contraception in women with inherited bleeding disorders

Burton¹,

Chi²,

Kadir³

2008

j fam plann reprod health care

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15-20% of cases and is characterised by abnormal structures of VWF that affect interaction between platelets, vessel walls and VWF. Type 3 VWD is the least common but most severe form of the disease. It is an autosomalrecessive disorder characterised by a severe deficiency of VWF and factor VIII.Haemophilia A and B are X-linked IBDs characterised by deficiencies of clotting factor VIII or IX, respectively. Men inherit the condition whilst women are affected as carriers. The incidence of haemophilia A and B in the general population is 1 in 101000 and 1 in 601000, respectively, 6 but the carrier rates in women are unknown. A wide range of factor VIII or IX levels have been reported among carriers of haemophilia, from the upper limit of normal through to very low levels similar to affected males caused by random X-chromosome inactivation (lyonisation). 7 Thus carriers may have an increased bleeding tendency and experience significant bleeding symptoms. In a study by Plug et al. carriers were found to experience more spontaneous and provoked haemorrhage compared to non-carriers in families with haemophilia. 8

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The VALUE National Hysterectomy Study: Description of the Patients and Their Surgery

Cited by 91 publications

References 0 publications

Clinical Profile of Uterine Prolapse Cases in South India

Clinical Profile of Uterine Prolapse Cases in South India

Treatment options for dysfunctional uterine bleeding: evaluation of clinical results

Gynaecological problems and choices for contraception in women with inherited bleeding disorders

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