The Validity of the Neuropathic Pain Scale for Assessing Diabetic Neuropathic Pain in a Clinical Trial

Jensen, Mark P.; Friedman, Michael; Bonzo, Daniel; Richards, P.

doi:10.1097/01.ajp.0000173018.64741.62

Cited by 77 publications

(52 citation statements)

References 20 publications

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“…Jensen et al [7] failed to demonstrate significant reduction in burning, pain when comparing opioids to placebo in their validation of the neuropathic pain score over 6 weeks. AKL gel did significantly reduce burning pain in the short and long term in this study.…”

Section: Discussionmentioning

confidence: 99%

“…Standard interventions included education regarding skin care during radiotherapy treatment, topical application of water or saline gauze soaks and sulfadiazine cream to areas of moist and dry desquamation, and use of oral analgesics. Potential subjects scored their pain at the start of the standard interventions using the University of Washington Neuropathic Pain Score (UWNPS) [7] and then again 2 days after the start of the standard interventions. If there was no decrease in the pain score, then they were eligible for this trial.…”

Section: Study Populationmentioning

confidence: 99%

See 1 more Smart Citation

Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study

Uzaraga

Gerbis

Holwerda

et al. 2011

Support Care Cancer

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Section: Discussionmentioning

confidence: 99%

Section: Study Populationmentioning

confidence: 99%

Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study

Uzaraga

Gerbis

Holwerda

et al. 2011

Support Care Cancer

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show abstract

“…[25] 'nın yaptığı diyabetik polinöropatik ağrılı 159 hastada, nöropatik ağrı komponentleri üzeri-ne analjezik tedavi etkinliğinin araştırıldığı çalışmada, NAS'nın nöropatik ağrı komponentlerini değerlendi-rebilen kapsamlı bir skala olduğu ve ayrıca tedavi ile nöropatik ağrıda saptanan değişiklerin takibinde de kullanılabileceği belirtilmiştir.…”

Section: Discussionunclassified

The Effects Of Pulsed Electromagnetic Field Treatment In Pain Due To Diabetic Polyneuropathy

Fezyioğlu¹,

Özdemir²,

Güldiken³

et al. 2009

TUTFD

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Objectives: Diabetic polyneuropathy is the most common and disabled complication of diabetes mellitus. Pharmacological treatment of diabetic neuropathy is limited because of the side efects of the drugs, used in the treatment of diabetic neuropthy. Alternative treatments are also used in diabetic neuropathy. Systemic side effects of non-pharmacological treatment modalities are rare. We evaluated the value of pulsed electromagnetic field treatment in patients with pain due to diabetic polyneuropathy. Patients and Methods:Symptomatic 95 patients were included in the study, and from these patients, 25 patients were randomized in pulsed electromagnetic field treatment group and 25 patients were randomized in placebo group. Pulsed electromagnetic field device was applied over both feet of the patients for one hour a day (during 10 days). Visual analog scale and neuropathic pain scale of all patients were performed before and after treatment and 6th week. Electroneuromyography was also performed before treatment and 6th week.Results: Improvement of pain determined by visual analog scale was 53% after treatment and 67% six weeks later. The improvement of visual analog scale scores were statistically significant in study group when compared with control subjects. Conclusion:The pulsed electromagnetic field may be an alternative treatment modality in diabetic patients with neuropathic pain.

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“…The NPS also includes one semi-structured question about temporal sequence that can distinguish neuropathic pain from non-neuropathic pain. [15][16][17] Acupuncture treatment was provided on a weekly basis with adjustments of frequency based on response. The patients were informed of the risks (local pain and bruising, minor bleeding, and lightheadedness) and signed consent for the acupuncture procedure.…”

Section: Methodsmentioning

confidence: 99%

Improvement of Painful Bortezomib-Induced Peripheral Neuropathy Following Acupuncture Treatment in a Case Series of Multiple Myeloma Patients

Bao

Lao

Medeiros

et al. 2012

Medical Acupuncture

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Background: Bortezomib-induced peripheral neuropathy (BIPN) is a common and severe dose-limiting side effect in multiple myeloma (MM) patients. Treatment with narcotics, antidepressants, and anticonvulsants are of limited value in reducing symptoms, and they have the potential for significant side effects. Acupuncture has been reported to be effective in treating neuropathic pain. There has been limited reporting on the effect of acupuncture in treating BIPN. Objective: The aim of this study was to report on the effect of acupuncture in treating BIPN. Design and Patients: This study was a retrospective case series of five MM patients experiencing painful BIPN. Intervention: The patients were treated with the same acupuncture protocol on a weekly basis, adjusted to twice a week or once every 2 weeks based on response. Treatment included insertion of disposable sterile acupuncture needles, which were retained for 25 minutes, at the following bilateral ear points: shen men, point zero, and two auricular points where electro-dermal signal was detected; and bilateral body acupuncture points: LI 4, TE 5, LI 11, ST 40, and Ba Feng in the upper and lower extremities. Main Outcome Measures: All patients were assessed for severity of painful BIPN using a 0-10 numeric pain scale, with one patient assessed using the Clinical Total Neuropathy Score, Functional Assessment of Cancer Therapy-Neurotoxicity questionnaire, and Neuropathy Pain Scale. Results: All five patients experienced immediate pain reduction after one acupuncture treatment. Two of three patients who had more than three acupuncture treatments experienced long-lasting pain reduction and function improvement. There were no adverse events associated with acupuncture. Conclusion: Acupuncture is a viable treatment option for MM patients experiencing painful BIPN. However, further prospective research is needed.

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The Validity of the Neuropathic Pain Scale for Assessing Diabetic Neuropathic Pain in a Clinical Trial

Abstract: These findings support the utility of the NPS for characterizing the multidimensional nature of the neuropathic pain experience and for detecting changes in neuropathic pain with treatment.

Cited by 77 publications

References 20 publications

Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study

Topical amitriptyline, ketamine, and lidocaine in neuropathic pain caused by radiation skin reaction: a pilot study

The Effects Of Pulsed Electromagnetic Field Treatment In Pain Due To Diabetic Polyneuropathy

Improvement of Painful Bortezomib-Induced Peripheral Neuropathy Following Acupuncture Treatment in a Case Series of Multiple Myeloma Patients

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