The utility of renal venous renin studies in selection of patients with renal artery stenosis for angioplasty

Goupil, Rémi; Cowley, Diane; Wolley, Martin; Ahmed, Ashraf; Gordon, Richard D.; Stowasser, Michael

doi:10.1097/hjh.0000000000000635

Cited by 5 publications

(1 citation statement)

References 45 publications

(50 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These trials have however selected patients for intervention largely on the basis of radiological criteria for renal artery stenosis rather than functional evidence of renin-driven hypertension. Observational evidence suggests that carefully demonstrated dominance of renin secretion from a kidney with an apparent stenotic artery may predict good blood pressure outcomes from intervention, including patients with CKD and resistant hypertension [310]. A reasonable approach would be to screen for renal artery stenosis in patients with mild CKD and other features suggestive of renovascular hypertension, such as deteriorating renal function with renin angiotensin system blocking drugs, peripheral vascular disease or the presence of a renal bruit.…”

Section: Pathogenesismentioning

confidence: 99%

Clinical and Physiological Aspects of Salt Sensitive Hypertension

Wolley¹

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Pathogenesismentioning

confidence: 99%

Clinical and Physiological Aspects of Salt Sensitive Hypertension

Wolley¹

Self Cite

View full text Add to dashboard Cite

show abstract

Resistant Hypertension and Chronic Kidney Disease: a Dangerous Liaison

Wolley

Stowasser

2016

Curr Hypertens Rep

View full text Add to dashboard Cite

Treatment-resistant hypertension is an increasingly recognised problem and is markedly over-represented in patients with chronic kidney disease (CKD). Recent evidence has clarified the heightened risk for both adverse renal and cardiovascular outcomes associated with resistant hypertension, even when blood pressure control is attained. The diagnosis of resistant hypertension in CKD is reliant on accurate blood pressure measurement, and out of office measurements are important due to the high prevalence of masked hypertension in these patients. Treatment strategies include careful dietary measures to restrict sodium intake, and a focus on improving adherence to antihypertensive medications. Medication choices should focus on a sensible foundation and then diuretic titration to combat the salt and volume retention inherent in CKD. In this review, we discuss the epidemiology, pathogenesis and consequences of resistant hypertension in CKD, and then review the optimal diagnostic and management strategies.

show abstract