The Use of Polylactic Acid to Obtain Biodegradable Medical Devices

Galimzyanova, R. Yu.; Mevliyanova,; Khisamieva, Dilyara R.; Pesternnikova, N.V.; Мусин, И Н; Lisanevich, Maria S.

doi:10.4028/www.scientific.net/kem.816.285

Cited by 5 publications

(2 citation statements)

References 10 publications

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“…The implanted material F1 contains 70% PLA, considered a biocompatible and utterly biodegradable material [ 49 ]; however, the degradability will depend on the molecular weight and the degree of crystallinity [ 50 ]. On the other hand, PCL has also considered a biocompatible and bioresorbable material with great potential in tissue engineering [ 51 ].…”

Section: Resultsmentioning

confidence: 99%

Polycaprolactone (PCL)-Polylactic Acid (PLA)-Glycerol (Gly) Composites Incorporated with Zinc Oxide Nanoparticles (ZnO-NPs) and Tea Tree Essential Oil (TTEO) for Tissue Engineering Applications

et al. 2022

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The search for new biocompatible materials that can replace invasive materials in biomedical applications has increased due to the great demand derived from accidents and diseases such as cancer in various tissues. In this sense, four formulations based on polycaprolactone (PCL) and polylactic acid (PLA) incorporated with zinc oxide nanoparticles (ZnO-NPs) and tea tree essential oil (TTEO) were prepared. The sol-gel method was used for zinc oxide nanoparticle synthesis with an average size of 11 ± 2 nm and spherical morphology. On the other hand, Fourier Transformed infrared spectroscopy (FTIR) showed characteristic functional groups for each composite component. The TTEO incorporation in the formulations was related to the increased intensity of the C-O-C band. The thermal properties of the materials show that the degradative properties of the ZnO-NPs decrease the thermal stability. The morphological study by scanning electron microscopy (SEM) showed that the presence of TTEO and ZnO-NPs act synergistically, obtaining smooth surfaces, whereas membranes with the presence of ZnO-NPs or TTEO only show porous morphologies. Histological implantation of the membranes showed biocompatibility and biodegradability after 60 days of implantation. This degradation occurs through the fragmentation of the larger particles with the presence of connective tissue constituted by type III collagen fibers, blood vessels, and inflammatory cells, where the process of resorption of the implanted material continues.

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Section: Resultsmentioning

confidence: 99%

Polycaprolactone (PCL)-Polylactic Acid (PLA)-Glycerol (Gly) Composites Incorporated with Zinc Oxide Nanoparticles (ZnO-NPs) and Tea Tree Essential Oil (TTEO) for Tissue Engineering Applications

et al. 2022

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“…The advantage of PLA is that it is obtained entirely from renewable sources (corn starch). Therefore, if polylactic acid is exposed to environmental conditions, it can decompose into carbon dioxide, methane and water in a period from several months to a year [5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Study of the Properties of Compositions Based on Polylactic Acid and Thermoplastic Starch

Galimzyanova

Khisamieva

Lisanevich

et al. 2021

KEM

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The use of thermoplastic starch in compositions based on polylactic acid is of interest from the point of view of controlling the physicomechanical properties of materials and the time of biodegradation. The effect of thermoplastic starch containing sorbitol and / or glycerin as plasticizers on the resistance of compositions based on polylactic acid to thermal and thermomechanical action was studied. The physicomechanical properties of the compositions and their resistance to biodegradation under composting conditions have also been determined.

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Peculiar crystallization and viscoelastic properties of polylactide/polytetrafluoroethylene composites induced by in-situ formed 3D nanofiber network

Jalali

Kim

Zolali

et al. 2020

Composites Part B: Engineering

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The Use of Polylactic Acid to Obtain Biodegradable Medical Devices

Cited by 5 publications

References 10 publications

Polycaprolactone (PCL)-Polylactic Acid (PLA)-Glycerol (Gly) Composites Incorporated with Zinc Oxide Nanoparticles (ZnO-NPs) and Tea Tree Essential Oil (TTEO) for Tissue Engineering Applications

Polycaprolactone (PCL)-Polylactic Acid (PLA)-Glycerol (Gly) Composites Incorporated with Zinc Oxide Nanoparticles (ZnO-NPs) and Tea Tree Essential Oil (TTEO) for Tissue Engineering Applications

Study of the Properties of Compositions Based on Polylactic Acid and Thermoplastic Starch

Peculiar crystallization and viscoelastic properties of polylactide/polytetrafluoroethylene composites induced by in-situ formed 3D nanofiber network

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