The use of new oral anticoagulants in surgery. Part 1

Pasechnik, I. N.

doi:10.17116/hirurgia2016272-75

Cited by 3 publications

(1 citation statement)

References 20 publications

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“…Предметом дискуссии яв-ляется выбор фармакологического препарата для профилактики венозного тромбоэмболизма. Антико-агулянты должны отвечать следующим требованиям: быть высокоэффективными, обладать низким риском кровотечений, простотой применения (пероральный способ употребления, отсутствие необходимости подбора дозы, специального мониторинга), возмож-ностью применения у пожилых людей и пациентов с печеночной и почечной недостаточностью [3,7].…”

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Efficacy and safety of new oral anticoagulants in the prevention of venous thromboembolism after orthopaedic surgery and their impact on the subsequent quality of life

Суковатых¹,

Иванов²,

Суковатых³

et al. 2017

Medical news of the North Caucasus

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Efficacy and safety of new oral anticoagulants in the prevention of venous thromboembolism after orthopaedic surgery and their impact on the subsequent quality of life

Суковатых¹,

Иванов²,

Суковатых³

et al. 2017

Medical news of the North Caucasus

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Current Issues of the Use and Efficacy of Direct Oral Anticoagulants According their Pharmacogenetic Features

Gantsgorn,

Safronenko,

Gubin

et al. 2023

BIOMEDICINE

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Despite the proven efficacy and relative safety of direct oral anticoagulants (DOAC), the issue of reducing the risk of complications associated with their use, depending on the genetic characteristics of patients, remains controversial. A personalized approach to the selection of DOAC should be developed. In this article, we review the available information on the feasibility of prescribing DOAC to patients with various diseases associated with hypercoagulation and on pharmacogenetic aspects of the DOAC application. The need for further research is substantiated, along with the importance of a wider introduction of the molecular-biological analysis of gene polymorphisms, whose presence affects the efficacy and safety of these drugs. In the course of the work, publications from the MedScape, PubMed, and eLIBRARY databases were analyzed.

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Some aspects of etiopathogenesis and treatment of the deep venous thrombosis of lower limbs

Radjabov

2022

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This review of the literature presents current understanding about the etiology, pathogenesis, complications, contemporary methods of treatment, outcomes, and the tactics of managing patients with deep venous thrombosis (DVT) of the lower limbs. Analysis of the data in a literature shows that despite significant advances in the diagnosis and treatment of DVT of the lower extremities, there are still many unresolved problems in terms of complex treatment and prevention of severe consequences of this pathology. The advent of new oral anticoagulants has led to a significant reduction in the incidence of post-thrombotic disease. However, the severity of post-thrombotic disease directly depends on the effectiveness of treatment in acute period of DVT, as well as the presence of hereditary risk factors. In this regard, the optimization of therapy in acute phase of disease and further rehabilitation therapy, management of patients in the long-term period, aimed at better recanalization of thrombosed segments of the lower limbs deep veins, seem to be relevant, requiring further research.

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The use of new oral anticoagulants in surgery. Part 1

Cited by 3 publications

References 20 publications

Efficacy and safety of new oral anticoagulants in the prevention of venous thromboembolism after orthopaedic surgery and their impact on the subsequent quality of life

Efficacy and safety of new oral anticoagulants in the prevention of venous thromboembolism after orthopaedic surgery and their impact on the subsequent quality of life

Current Issues of the Use and Efficacy of Direct Oral Anticoagulants According their Pharmacogenetic Features

Some aspects of etiopathogenesis and treatment of the deep venous thrombosis of lower limbs

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