The Use of Botulinum Toxin to Treat Strabismus Following Retinal Detachment Surgery

Diplopia following retinal detachment repair: prisms or surgery long term?

“…In a 24-year retrospective review, 140 patients received botulinum toxin injections to control their diplopia following retinal detachment surgery. 9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion.…”

“…9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion. 8 Complications from the injections were seen in only 2.9% of patients.…”

“…8 The reported incidence of diplopia following retinal detachment surgery has varied from 1.5% to 25%. 8,9 Evidence of the incidence rate comes only from retrospective case reviews from various hospitals. As case reviews report a variable follow-up time, this might contribute to the variable incidence rate, with some units that specialise in VR surgery and perform significantly more surgeries having a lower rate of complications.…”

“…8 In contrast, another study concluded that surgical correction of diplopia was technically difficult to perform and the results were less predictable than other forms of strabismus surgery. 9 A 20-year retrospective review of patients who underwent strabismus surgery following retinal detachment repair identified 25 patients; the average time between the retinal detachment surgery and the onset of diplopia was 4 months (range 0-42 months), and the average time between retinal detachment and strabismus surgery was 52 months (range 3-480 months). 10 All the patients had undergone scleral buckling procedures, and in addition 48% had cryotherapy.…”

Diplopia following retinal detachment repair: prisms or surgery long term?

“…In a 24-year retrospective review, 140 patients received botulinum toxin injections to control their diplopia following retinal detachment surgery. 9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion.…”

“…9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion. 8 Complications from the injections were seen in only 2.9% of patients.…”

“…8 The reported incidence of diplopia following retinal detachment surgery has varied from 1.5% to 25%. 8,9 Evidence of the incidence rate comes only from retrospective case reviews from various hospitals. As case reviews report a variable follow-up time, this might contribute to the variable incidence rate, with some units that specialise in VR surgery and perform significantly more surgeries having a lower rate of complications.…”

“…8 In contrast, another study concluded that surgical correction of diplopia was technically difficult to perform and the results were less predictable than other forms of strabismus surgery. 9 A 20-year retrospective review of patients who underwent strabismus surgery following retinal detachment repair identified 25 patients; the average time between the retinal detachment surgery and the onset of diplopia was 4 months (range 0-42 months), and the average time between retinal detachment and strabismus surgery was 52 months (range 3-480 months). 10 All the patients had undergone scleral buckling procedures, and in addition 48% had cryotherapy.…”

Botulinum toxin for the treatment of strabismus

“…Botulinum toxin has become recognised and accepted as both an adjunct and alternative to strabismus surgery in many types of strabismus (Bunting 2013;Campos 2000;Crouch 2006;Dawson 1999;Dawson 2004a;Dawson 2004b;Dawson 2005;Dawson 2012;Gardner 2013;Holmes 2001;Kerr 2001;Marsh 2003;McNeer 2003;Ozkan 2006;Rayner 1999;Rowe 2004;Sabetti 2003;Spencer 1997;Tejedor 2001). Diagnostic uses of botulinum toxin include investigation of postoperative diplopia (double vision), to detect whether fusion (which contributes to binocular vision) is present preoperatively, to di erentially diagnose between a part and complete sixth nerve palsy, to aid in the prediction of surgical results for incomitant deviations and to help in the investigation of a possible slipped muscle following surgery.…”

Diplopia following retinal detachment repair: prisms or surgery long term?

“…In a 24-year retrospective review, 140 patients received botulinum toxin injections to control their diplopia following retinal detachment surgery. 9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion.…”

“…9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion. 8 Complications from the injections were seen in only 2.9% of patients.…”

“…8 The reported incidence of diplopia following retinal detachment surgery has varied from 1.5% to 25%. 8,9 Evidence of the incidence rate comes only from retrospective case reviews from various hospitals. As case reviews report a variable follow-up time, this might contribute to the variable incidence rate, with some units that specialise in VR surgery and perform significantly more surgeries having a lower rate of complications.…”

“…8 In contrast, another study concluded that surgical correction of diplopia was technically difficult to perform and the results were less predictable than other forms of strabismus surgery. 9 A 20-year retrospective review of patients who underwent strabismus surgery following retinal detachment repair identified 25 patients; the average time between the retinal detachment surgery and the onset of diplopia was 4 months (range 0-42 months), and the average time between retinal detachment and strabismus surgery was 52 months (range 3-480 months). 10 All the patients had undergone scleral buckling procedures, and in addition 48% had cryotherapy.…”

Botulinum toxin for the treatment of strabismus

“…Botulinum toxin has become recognised and accepted as both an adjunct and alternative to strabismus surgery in many types of strabismus (Bunting 2013;Campos 2000;Crouch 2006;Dawson 1999;Dawson 2004a;Dawson 2004b;Dawson 2005;Dawson 2012;Gardner 2013;Holmes 2001;Kerr 2001;Marsh 2003;McNeer 2003;Ozkan 2006;Rayner 1999;Rowe 2004;Sabetti 2003;Spencer 1997;Tejedor 2001). Diagnostic uses of botulinum toxin include investigation of postoperative diplopia (double vision), to detect whether fusion (which contributes to binocular vision) is present preoperatively, to di erentially diagnose between a part and complete sixth nerve palsy, to aid in the prediction of surgical results for incomitant deviations and to help in the investigation of a possible slipped muscle following surgery.…”

Diplopia following retinal detachment repair: prisms or surgery long term?

“…In a 24-year retrospective review, 140 patients received botulinum toxin injections to control their diplopia following retinal detachment surgery. 9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion.…”

“…9 To achieve lasting symptomatic relief 1 injection was sufficient in 23.6% of cases, with 50.5% requiring 2 injections. 9 The authors identified after a multivariate analysis that visual acuity in the originally affected eye was the only factor associated with lack of restoration of fusion. 8 Complications from the injections were seen in only 2.9% of patients.…”

“…8 The reported incidence of diplopia following retinal detachment surgery has varied from 1.5% to 25%. 8,9 Evidence of the incidence rate comes only from retrospective case reviews from various hospitals. As case reviews report a variable follow-up time, this might contribute to the variable incidence rate, with some units that specialise in VR surgery and perform significantly more surgeries having a lower rate of complications.…”

“…8 In contrast, another study concluded that surgical correction of diplopia was technically difficult to perform and the results were less predictable than other forms of strabismus surgery. 9 A 20-year retrospective review of patients who underwent strabismus surgery following retinal detachment repair identified 25 patients; the average time between the retinal detachment surgery and the onset of diplopia was 4 months (range 0-42 months), and the average time between retinal detachment and strabismus surgery was 52 months (range 3-480 months). 10 All the patients had undergone scleral buckling procedures, and in addition 48% had cryotherapy.…”

Botulinum toxin for the treatment of strabismus

“…Botulinum toxin has become recognised and accepted as both an adjunct and alternative to strabismus surgery in many types of strabismus (Bunting 2013;Campos 2000;Crouch 2006;Dawson 1999;Dawson 2004a;Dawson 2004b;Dawson 2005;Dawson 2012;Gardner 2013;Holmes 2001;Kerr 2001;Marsh 2003;McNeer 2003;Ozkan 2006;Rayner 1999;Rowe 2004;Sabetti 2003;Spencer 1997;Tejedor 2001). Diagnostic uses of botulinum toxin include investigation of postoperative diplopia (double vision), to detect whether fusion (which contributes to binocular vision) is present preoperatively, to di erentially diagnose between a part and complete sixth nerve palsy, to aid in the prediction of surgical results for incomitant deviations and to help in the investigation of a possible slipped muscle following surgery.…”