The use and misuse of oxytocin: a study in rural Karnataka, India

Karachiwala, Baneen; Matthews, Zoë; Kilaru, Asha

doi:10.1186/1753-6561-6-s1-p12

Cited by 4 publications

(2 citation statements)

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“…The ndings suggest that oxytocin is being overused in both government and private healthcare settings, highlighting the necessity for adherence to clinical protocols and guidelines to ensure safe motherhood. 21 The study complements the comprehensive study on maternal and neonatal health in Shrawasti district, which resulted in signi cant reductions in adverse outcomes like stillbirths, asphyxia, and post-partum haemorrhage through enhanced awareness initiatives, revised administration practices of oxytocin, and accountability measures at administrative levels.…”

Section: Discussionmentioning

confidence: 95%

Assessing the Effect of Integrated Health Interventions on Maternal and Neonatal Health Outcomes in an aspirational district of Uttar Pradesh: A mixed method study

Yadav,

Ahmad,

Lohani

et al. 2024

Preprint

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Introduction: India has made significant progress in maternal and neonatal health, yet challenges persist. This study examines Shrawasti, a Uttar Pradesh district, to understand strategies for enhancing maternal and neonatal health. It particularly focuses on birth asphyxia and postpartum haemorrhage due to oxytocin misuse. Objective: To compare pre- and post-intervention maternal and newborn complications in Shrawasti and identify factors decreasing postpartum haemorrhage, newborn deaths, stillbirths, and birth asphyxia. The study aims to elucidate effective interventions for improving maternal and neonatal health. Methodology: A retrospective observational study collected data from labour rooms and the Special Newborn Care Unit in Shrawasti. In-depth interviews with healthcare workers provided qualitative insights. Interventions were implemented based on initial findings and evaluated through systematic data organization and assessment. Results: Post-intervention, there was a significant reduction in stillbirths, asphyxia, and postpartum haemorrhage. Asphyxia decreased from 74.5% to 33.2%, stillbirths from 28.5% to 12.5%, and postpartum haemorrhage from 53.8% to 26%. Qualitative analysis highlighted improved healthcare practices, training effectiveness, staff behaviour shifts, and enhanced patient awareness. Documentation and monitoring practices also improved significantly. Conclusion: Interventions significantly transformed maternal and neonatal healthcare in Shrawasti. Enhanced awareness, revised practices in oxytocin administration, effective training, and improved documentation were pivotal in reducing adverse outcomes. Addressing challenges through targeted interventions is crucial for better healthcare outcomes.

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Section: Discussionmentioning

confidence: 95%

Assessing the Effect of Integrated Health Interventions on Maternal and Neonatal Health Outcomes in an aspirational district of Uttar Pradesh: A mixed method study

Yadav,

Ahmad,

Lohani

et al. 2024

Preprint

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“…The study found moderate levels of availability of oxytocin (42.7%) in the study pharmacies, slightly more in the rural areas than in the urban ones. There is a well-developed maternal child health program in India and through this oxytocin is widely available at primary public health facilities, but unqualified staff and poor management of stocks and inadequate storage conditions all contribute towards poor availability of oxytocin in public health facilities and this may account for its availability in the private pharmacies [ 38 - 42 ]. Additionally there is evidence that its availability in private pharmacies has contributed to its misuse to induce or speed labours [ 38 - 41 ].…”

Section: Discussionmentioning

confidence: 99%

Availability of brands of six essential medicines in 124 pharmacies in Maharashtra

Millard

Kadam

Mahajan

et al. 2018

Journal of Global Health

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BackgroundThe aim of this study is to assess the availability and rational use of six essential medicines in private retail outlets in Maharashtra state. The study focuses on the range of brands for each medicine, and the availability of these brands in the pharmacies. The medicines were chosen because they are included in the World Health Organization’s (WHO) essential medicines list (EML), the Indian national and Maharashtra state medicines list, and are all included in existing Indian public health initiatives and national disease control programmes.MethodsData was gathered on the availability of the medicines and the range and frequency of brands in 124 private retail pharmacies between January and May 2012. As there is currently no centralised database in India of available pharmaceutical brands, we collected data on the range of products of the 6 essential medicines available in the Indian market by consulting three open access Indian pharmaceutical databases, CIMS India, Medindia, and Medguide, and the commercial database, Pharmatrac; we compared this data with the results of the survey. The six essential medicines used in this study are: artemisinin (malaria), lamivudine (HIV/AIDS), rifampicin (tuberculosis control), oxytocin (reproductive health), fluoxetine (mental health) and metformin (diabetes).ResultsThe study found that for each of the selected medicines there were multiple approved products listed in Indian databases, 2186 in total. The Pharmatrac database lists only 1359 brands of the selected medicines; 978 (72%) of these had zero sales in 2011-2012. Our survey found very low availability of the brands: 17% Pharmatrac marketed brands (163/978) and 12% of all Pharmatrac brands (163/1359) were available. Metformin was the only medicine with high availability in the study pharmacies at 91%, Rifampacin was the second highest at 64.5%; the other four medicines were available in less than half the pharmacies. A small number of brands were dominating the market.Conclusionthe survey shows that market competition has generated a large number of brands of the six study medicines but this has not translated into sufficient availability of these medicines in the study pharmacies. The data calls for a review of available brands, taking into consideration levels of sale and grounds for approval, and the setting up of a centralised database of registered pharmaceutical products.

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Barriers to optimal and appropriate use of uterotonics during active labour and for prevention of postpartum haemorrhage in public health care facilities: An exploratory study in five states of India

Singh

Chandhiok

Dubey

et al. 2021

Sexual & Reproductive Healthcare

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The use and misuse of oxytocin: a study in rural Karnataka, India

Cited by 4 publications

References 0 publications

Assessing the Effect of Integrated Health Interventions on Maternal and Neonatal Health Outcomes in an aspirational district of Uttar Pradesh: A mixed method study

Assessing the Effect of Integrated Health Interventions on Maternal and Neonatal Health Outcomes in an aspirational district of Uttar Pradesh: A mixed method study

Availability of brands of six essential medicines in 124 pharmacies in Maharashtra

Barriers to optimal and appropriate use of uterotonics during active labour and for prevention of postpartum haemorrhage in public health care facilities: An exploratory study in five states of India

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