The Tryton Side Branch Stent™ for the treatment of coronary bifurcation lesions

Abstract

Coronary bifurcation lesions account for approximately 15% of all percutaneous coronary interventions (PCI) performed. Although clinical outcomes after PCI have been improved considerably, PCI of bifurcation lesions remains to be associated with adverse clinical events, when compared with non-bifurcation PCI. Therefore, several dedicated bifurcation devices have been developed to improve clinical outcomes. The Tryton Side Branch Stent(™) is such device and is used in combination with a regular tubular balloon expandable stent in the main branch. Multiple single and multicenter registries and a patient pooled analysis including 900 patients have shown promising results regarding clinical outcomes after bifurcation PCI with Tryton. The pivotal Tryton IDE randomized trial is currently underway comparing the Tryton stent with side branch balloon angioplasty as side branch treatment in bifurcation lesions challenging the current dogma of provisional single stent strategy as treatment for coronary bifurcation lesions.

Comparison between two‐ and three‐dimensional quantitative coronary angiography bifurcation analyses for the assessment of bifurcation lesions: A subanalysis of the TRYTON pivotal IDE coronary bifurcation trial

“…The details of the Tryton side branch stent were described elsewhere . The Tryton stent is a balloon‐expandable cobalt chromium (CoCr) bare‐metal stent with strut thickness of 84 μm.…”

Differences in rotational positioning and subsequent distal main branch rewiring of the Tryton stent: An optical coherence tomography and computational study

“…The Tryton Side Branch Stent™ is discussed in detail elsewhere . Briefly, it is a cobalt‐chromium bare metal stent with a strut thickness of 84 µm (0.0033 in.).…”

“…The Tryton Side Branch Stent™ has been developed for a “simplified culotte” technique with the hope to improve outcomes of percutaneous coronary interventions (PCIs) of bifurcation lesions . The Tryton stent shares its proximal part with the main branch stent proximal to the bifurcation.…”

“…The Tryton stent shares its proximal part with the main branch stent proximal to the bifurcation. The Tryton stent consists of three zones : a proximal main branch zone, the central transition zone, and a distal side branch zone. The proximal main branch zone has two proximal “wedding bands”, from which three undulating fronds connect these wedding bands with three “panels” of the transition zone.…”

TCT-345 Detailed Segmental Comparison Between a Dedicated Bifurcation Stent and Balloon Angioplasty Using Intravascular Ultrasound and Three-dimensional Quantitative Coronary Angiography: a Subgroup Analysis of the Tryton IDE Randomized Trial

“…There are many different two-stent techniques, all with their own technical limitations, and operators experience and skills may play an important role in procedural success [6]. The baremetal Tryton Side Branch Stent TM (Tryton Medical, Durham, NC) was developed to overcome some of the technical limitations of the two-stent approach [7][8][9][10][11][12][13][14]. Recently, the device was evaluated in the randomized Tryton Investigational Device Exemption (IDE) trial, the first trial powered for clinical endpoints comparing a dedicated bifurcation stent against side branch balloon angioplasty (SBBA) as part of a provisional single stent strategy.…”