The Treatment of Total Hyphemia with Fibrinolysin (Plasmin)

The Surgical Management of Total Hyphæma

“…The management of total secondary hyphama has been the subject of controversy (Scheie, 1961). Suggested therapeutic regimes have ranged widely from conservatism (Gregersen, 1962) to the proposition of Sears Currently, most of the disagreement on therapy centres around surgical timing and technique, and for this reason, the rationale .of the method used in this series, is presented and discussed in detail.…”

The Surgical Management of Total Hyphæma

“…The management of total secondary hyphama has been the subject of controversy (Scheie, 1961). Suggested therapeutic regimes have ranged widely from conservatism (Gregersen, 1962) to the proposition of Sears Currently, most of the disagreement on therapy centres around surgical timing and technique, and for this reason, the rationale .of the method used in this series, is presented and discussed in detail.…”

Erythrocyte Resorption From a Clotted Hyphema in Rabbit Eyes

“…By injecting plasmin directly into the anterior chamber of the eye, one may reasonably presume that instantaneous neutralization of antiplasmin substances will be avoided, leaving the plasmin free to participate in the fibrinolytic process. Thrombolysin is well tolerated when injected into the anterior chamber, except in concentrations above 10000 MSD-units per ml (Scheie et al 1961).…”

Fibrinolysis and Hyphema

“…As ,>Thrombolysin<< acts more powerfully in humans, confirmation is obtained for Scheie et .al. results (14). I t is worth giving serious consideration to the use of >>Thrombolysin(< irrigation as a method of immediate treatment in severe cases of hyphema.…”

“…Scheie et al (14) in 1961 irrigated the anterior chamber in 2 patients with total hyphema with Thrombolysin, 1250 MSD-units/ml, and obtained lysis with no serious complications. Kabikinas has not been used previously in ophthalmology, as far as is known.…”

The Surgical Management of Total Hyphæma

“…The management of total secondary hyphama has been the subject of controversy (Scheie, 1961). Suggested therapeutic regimes have ranged widely from conservatism (Gregersen, 1962) to the proposition of Sears Currently, most of the disagreement on therapy centres around surgical timing and technique, and for this reason, the rationale .of the method used in this series, is presented and discussed in detail.…”

Erythrocyte Resorption From a Clotted Hyphema in Rabbit Eyes

“…By injecting plasmin directly into the anterior chamber of the eye, one may reasonably presume that instantaneous neutralization of antiplasmin substances will be avoided, leaving the plasmin free to participate in the fibrinolytic process. Thrombolysin is well tolerated when injected into the anterior chamber, except in concentrations above 10000 MSD-units per ml (Scheie et al 1961).…”

Fibrinolysis and Hyphema

“…As ,>Thrombolysin<< acts more powerfully in humans, confirmation is obtained for Scheie et .al. results (14). I t is worth giving serious consideration to the use of >>Thrombolysin(< irrigation as a method of immediate treatment in severe cases of hyphema.…”

“…Scheie et al (14) in 1961 irrigated the anterior chamber in 2 patients with total hyphema with Thrombolysin, 1250 MSD-units/ml, and obtained lysis with no serious complications. Kabikinas has not been used previously in ophthalmology, as far as is known.…”

The Surgical Management of Total Hyphæma

“…The management of total secondary hyphama has been the subject of controversy (Scheie, 1961). Suggested therapeutic regimes have ranged widely from conservatism (Gregersen, 1962) to the proposition of Sears Currently, most of the disagreement on therapy centres around surgical timing and technique, and for this reason, the rationale .of the method used in this series, is presented and discussed in detail.…”

Erythrocyte Resorption From a Clotted Hyphema in Rabbit Eyes

“…By injecting plasmin directly into the anterior chamber of the eye, one may reasonably presume that instantaneous neutralization of antiplasmin substances will be avoided, leaving the plasmin free to participate in the fibrinolytic process. Thrombolysin is well tolerated when injected into the anterior chamber, except in concentrations above 10000 MSD-units per ml (Scheie et al 1961).…”

Fibrinolysis and Hyphema

“…As ,>Thrombolysin<< acts more powerfully in humans, confirmation is obtained for Scheie et .al. results (14). I t is worth giving serious consideration to the use of >>Thrombolysin(< irrigation as a method of immediate treatment in severe cases of hyphema.…”

“…Scheie et al (14) in 1961 irrigated the anterior chamber in 2 patients with total hyphema with Thrombolysin, 1250 MSD-units/ml, and obtained lysis with no serious complications. Kabikinas has not been used previously in ophthalmology, as far as is known.…”