The Third-Generation Cephalosporin Use in a Regional General Hospital in Indonesia

Yulia, Rika; Giovanny, Beatrix Eyleen; Utami, Sylvia Putri; Alkindi, Fawandi Fuad; Herawati, Fauna; Jaelani, Abdul Kadir

doi:10.7897/2230-8407.099185

Cited by 5 publications

(5 citation statements)

References 9 publications

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“…The study by Van Limburg et al showed that 88% of educational hospitals and 73% of non-educational hospitals implement antibiotic formulary for antibiotic stewardship program [ 25 ]. Guidelines for Antibiotic Use is a guideline according to the types of infections in patients or as prophylaxis for surgery [ 27 , 28 ]; therefore an ARCP can assist in the selection of antibiotics. According to the IDSA's guideline, the development of Guidelines for Antibiotic Use from recent literature and antibiotic resistance reports is an additional component for implementing antibiotic stewardship.…”

Section: Discussionmentioning

confidence: 99%

Interview-based cross-sectional needs assessment to advance the implementation of an effective antibiotic stewardship program in Indonesian hospitals

et al. 2020

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Section: Discussionmentioning

confidence: 99%

Interview-based cross-sectional needs assessment to advance the implementation of an effective antibiotic stewardship program in Indonesian hospitals

et al. 2020

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“…Apart from its effectiveness, antibiotics also carry a microbial resistance risk. Unnecessary antibiotic prescription is the most common sign of inappropriate antibiotic use [23][24][25][26][27]. Antibiotics should not be carelessly prescribed for acute gastroenteritis since the misuse of antibiotics contributes to antibiotic resistance, one of which is Clostridium difficile infection.…”

Section: Discussionmentioning

confidence: 99%

The ANTIBIOTIC CONSUMPTION AT A PEDIATRIC WARD AT A PUBLIC HOSPITAL IN INDONESIA

Herawati

Upa

Yulia

et al. 2019

Asian J Pharm Clin Res

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Objective: The aims of the study are to describe how antibiotics were used in a pediatric ward and to observe how they were prescribed for infectious diarrheas of bacterial origin indication. Diarrhea or acute gastroenteritis is one of the most common infection diagnoses observed among the hospitalized children. Rehydration therapy is the key treatment for children with diarrhea. With the zinc supplement, the duration of the hospital stay can be reduced. Thus, the decision whether the local or regional health authorities need to provide an antibiotic treatment depends on the etiology of the disease, the patient’s nutritional history and immunological status, and eventually, the severity of the disease. Good anamneses and diagnoses are essential to decide whether antibiotic treatment is required. Methods: The observation in this study consists of two phases. The first-phase observation was taken from the diagnosis and the number of antibiotics used in 2016 retrospectively calculated from each of the patients’ medical records. Meanwhile, the second phase descriptive observation was prospectively drawn from the stool culture and the number of antibiotics prescribed to 21 inpatient diarrhea children between May 2017 and December 2017. The amount of antibiotic consumption was administered based on defined daily dose (DDD) and days of therapy (DOT). Results: In 2016, 56% (828/1476) of the patients received antibiotic prescriptions. On average, the DDD per 100 bed-days was 45.57. In the prospective study, six of 21 patients with diarrhea were prescribed antibiotics intravenously. The DOT was 3.5 days and the DDD for these patients was 12.10/100 bed-days. Conclusion: There was a high consumption rate of antibiotics which was not indicated in each patient’s etiology of diarrhea in the hospital during the period. Thus, the recommendation is to encourage health authorities to judiciously prescribe antibiotics according to the guidelines.

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“…It is stated in their WHO report on surveillance of antibiotic consumption that the incidence of antibiotic resistance has increased rapidly in Asia, with the highest incidence in Southeast Asia [2,3]. Overprescribing [4], and the use of monotherapy broad-spectrum antibiotics [5,6] are the main causes of antibiotic resistance [7,8]. The reasons for antibiotic overprescribing and the use of monotherapy broad-spectrum antibiotics are the massive antibiotics revenue [9,10], the lack of supervision in antibiotic distribution by the regulatory authorities [11], physician-related factors, and patient-related factors [12].…”

Section: Introductionmentioning

confidence: 99%

Educational Video Improves Knowledge about Outpatients’ Usage of Antibiotics in Two Public Hospitals in Indonesia

et al. 2021

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The inappropriate use or misuse of antibiotics, particularly by outpatients, increases antibiotic resistance. A lack of public knowledge about “Responsible use of antibiotics” and “How to obtain antibiotics” is a major cause of this. This study aimed to assess the effectiveness of an educational video about antibiotics and antibiotic use to increase outpatients’ knowledge shown in two public hospitals in East Java, Indonesia. A quasi-experimental research setting was used with a one-group pre-test—post-test design, carried out from November 2018 to January 2019. The study population consisted of outpatients to whom antibiotics were prescribed. Participants were selected using a purposive sampling technique; 98 outpatients at MZ General Hospital in the S regency and 96 at SG General Hospital in the L regency were included. A questionnaire was used to measure the respondents’ knowledge, and consisted of five domains, i.e., the definition of infections and antibiotics, obtaining the antibiotics, directions for use, storage instructions, and antibiotic resistance. The knowledge test score was the total score of the Guttman scale (a dichotomous “yes” or “no” answer). To determine the significance of the difference in knowledge before and after providing the educational video and in the knowledge score between hospitals, the (paired) Student’s t-test was applied. The educational videos significantly improved outpatients’ knowledge, which increased by 41% in MZ General Hospital, and by 42% in SG General Hospital. It was concluded that an educational video provides a useful method to improve the knowledge of the outpatients regarding antibiotics.

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The Third-Generation Cephalosporin Use in a Regional General Hospital in Indonesia

Cited by 5 publications

References 9 publications

Interview-based cross-sectional needs assessment to advance the implementation of an effective antibiotic stewardship program in Indonesian hospitals

Interview-based cross-sectional needs assessment to advance the implementation of an effective antibiotic stewardship program in Indonesian hospitals

The ANTIBIOTIC CONSUMPTION AT A PEDIATRIC WARD AT A PUBLIC HOSPITAL IN INDONESIA

Educational Video Improves Knowledge about Outpatients’ Usage of Antibiotics in Two Public Hospitals in Indonesia

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