2021
DOI: 10.23838/pfm.2020.00191 View full text |Buy / Rent full text
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Abstract: A tic is a sudden, rapid, recurrent, and nonrhythmic motor movement and vocalization. In Tourette's disorder (TD), the tics may wax and wane in frequency and severity but persist for more than one year since the first tic onset. TD may have a high spontaneous remission rate. However, in some patients, tic symptoms persist even after adulthood. Since tic symptoms develop from a very young age and have wax and wane patterns during the development period, uncontrolled symptoms can cause both subjective distress a… Show more

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“…To date, no curative or speci c treatments for tic disorders have been developed 1 . Various genetic, epigenetic, and environmental factors are responsible for the disorder 2 . However, due to the ambiguity caused by small sample sizes or phenotype de nitions in previous studies, no diagnostic markers or genetic or epigenetic tic disorder biomarkers associated with the treatment and prognosis of tic disorders have been identi ed 3 .…”
Section: Introductionmentioning
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“…To date, no curative or speci c treatments for tic disorders have been developed 1 . Various genetic, epigenetic, and environmental factors are responsible for the disorder 2 . However, due to the ambiguity caused by small sample sizes or phenotype de nitions in previous studies, no diagnostic markers or genetic or epigenetic tic disorder biomarkers associated with the treatment and prognosis of tic disorders have been identi ed 3 .…”
Section: Introductionmentioning