The theory of evolution

Bennett, Keith

doi:10.1016/s0262-4079(10)62530-4

Cited by 8 publications

(8 citation statements)

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“…Chemoinformatics, which unites chemical information on drug compounds and biological information on drug target, would also be applied to dosage design of candidate compounds, proper use of medicines and discovery of new chemical entities. Fusion with chemoinformatics and living body system information obtained by metabolomics [190] and glycomics [191], which is rapidly developing, would make us expect tailor-made or personalized medicine [192] in the future.…”

Section: Resultsmentioning

confidence: 99%

<Review> A Mini-review on Chemoinformatics Approaches for Drug Discovery

Kawashita

Yamasaki

Miyao

et al. 2015

J. Comput. Aided Chem.

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Section: Resultsmentioning

confidence: 99%

<Review> A Mini-review on Chemoinformatics Approaches for Drug Discovery

Kawashita

Yamasaki

Miyao

et al. 2015

J. Comput. Aided Chem.

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“…In any case, it happens-relatively often actually-that the copies of DNA have errors, most of them with no influence, but sometimes they change the organism, which is then tested by the next higher wholeness, the ecosystem, that eliminates bad mutations and keeps positive ones for later generations. About the chaotic patterns of this process, see [60]. All this is part of evolution for which some also claim the need for additional explanations to pure Darwinism (e.g., the already mentioned vitalists).…”

Section: A Global Vista: Options For a Better Philosophymentioning

confidence: 99%

Holism and Reductionism: How to Get the Balance Right

Abächerli¹

2016

OALib

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This is an extensive study of the conditions that allow or impede reductionism. After an overview of the different anti-reductionist conditions in approaches like holism, downward causation, emergence, supervenience, and several forms of uncertainty and sensitive dependence, a more detailed analysis of downward causation and holism is presented. For the latter, strong and numerous arguments could be identified why the whole is more than the sum of its parts. However, the examination of the case of official big bang theory, specifically a finite universe based on ultimate particles, allows the formulation of a potential reductionist theory in principle. The key notions for the further argumentation are different forms of infinity: the infinitely small, the infinitely big and the infinity of points in a continuous space-time, even if this is finite in its extension. Several cases are presented in which systems are at the same time holistic and reductionist if conditions of infinity are applied. This is identified as a natural ontological property of such systems as soon as infinity intervenes. The final conclusion, however, is that the certainties of reductionism are methodologically only useful on very small objects. In the macroscopic world the only way to influence things is by controlling or directing the processes by downward causation, which is based on the elimination or management of uncertainties at higher non-microscopic levels.

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“…Evolutionary studies may emphasise chance, or unrepeatable contingency, as in Gould’s [ 1 ] classic study of the Burgess Shales, and this approach can find its extreme expression in attempts to apply chaos theory to evolution [ 2 ]. On the other hand studies may focus on repeatability, or determinism, in evolution [ 3 – 5 ] as this can enable workers to elucidate the factors which that are impacting on the evolutionary process.…”

Section: Introductionmentioning

confidence: 99%

“…Central to the “chance versus determinism” debate is the extent to which intraspecific microevolutionary trends can predict interspecific macroevolutionary trends. An approach centred on punctuated equilibria [ 1 , 2 , 9 ] would minimise this predictability, while an approach centred on natural selection driven evolution would not.…”

Section: Introductionmentioning

confidence: 99%

Predictability in evolution: Adaptation of the Bonaire anole (Anolis bonairensis) to an extreme environment

Thorpe

2017

PLoS ONE

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The extent to which evolution is deterministic (predictable), or random, is a fundamental question in evolution. This case study attempts to determine the extent to which interspecific divergence can be predicted from intraspecific trends related species. The mountainous Lesser Antilles are occupied by one or two anole species with very substantial intraspecific differences in the quantitative traits between xeric and rainforest habitats. These ecologically determined differences tend to be in parallel in each island species. A related species (Anolis bonairensis) lives on the far more xeric island of Bonaire, and this study tests the extent to which its interspecific divergence in hue and pattern traits can be predicted from the parallel intraspecific variation exhibited in Lesser Antillean anoles. Regression against a multivariate climate variable suggests that the hue and pattern of the Bonaire anole are consistently predicted from the ecologically determined intraspecific variation of its Lesser Antillean relatives. However, this predictability may be less consistent with other character systems, for example, scalation.

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The theory of evolution

Cited by 8 publications

References 0 publications

<Review> A Mini-review on Chemoinformatics Approaches for Drug Discovery

<Review> A Mini-review on Chemoinformatics Approaches for Drug Discovery

Holism and Reductionism: How to Get the Balance Right

Predictability in evolution: Adaptation of the Bonaire anole (Anolis bonairensis) to an extreme environment

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