The taxonomic revision of Alcea and Althaea (Malvaceae) in Turkey

Uzunhisarcikli, M. Erkan; Vural, Mecit

doi:10.3906/bot-1108-11

Cited by 12 publications

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“…The genus Alcea has about 70 species worldwide and is distributed in Mediterranean and Iran-Turanian phytogeographical region [ 4 , 5 ]. Alcea is represented by 18 species in the Flora of Turkey [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of Alcea fasciculiflora from Turkey?

et al. 2022

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The bioactive content, antioxidant properties, and enzyme inhibition properties of extracts of Alcea fasciculiflora from Turkey prepared with different solvents (water, methanol, ethyl acetate) and extraction methods (maceration, soxhlet, homogenizer assisted extraction, and ultrasound assisted extraction) were examined in this study. UHPLC-HRMS analysis detected or annotated a total of 50 compounds in A. fasciculiflora extracts, including 18 hydroxybenzoic and hydroxycinnamic acids, 7 Hexaric acids, 7 Coumarins, 15 Flavonoids, and 3 hydroxycinnamic acid amides. The extracts had phenolic and flavonoid levels ranging from 14.25 to 24.87 mg GAE/g and 1.68 to 25.26 mg RE/g, respectively, in the analysis. Both DPPH and ABTS tests revealed radical scavenging capabilities (between 2.63 and 35.33 mg TE/g and between 13.46 and 76.27 mg TE/g, respectively). The extracts had reducing properties (CUPRAC: 40.38–78 TE/g and FRAP: 17.51–42.58 TE/g). The extracts showed metal chelating activity (18.28–46.71 mg EDTAE/g) as well as total antioxidant capacity (phosphomolybdenum test) (0.90–2.12 mmol TE/g). DPPH, ABTS, FRAP, and metal chelating tests indicated the water extracts to be the best antioxidants, while the ethyl acetate extracts had the highest overall antioxidant capacity regardless of the extraction technique. Furthermore, anti-acetylcholinesterase activity was identified in all extracts (0.17–2.80 mg GALAE/g). The water extracts and the ultrasound-assisted ethyl acetate extract were inert against butyrylcholinesterase, but the other extracts showed anti-butyrylcholinesterase activity (1.17–5.80 mg GALAE/g). Tyrosine inhibitory action was identified in all extracts (1.79–58.93 mg KAE/g), with the most effective methanolic extracts. Only the ethyl acetate and methanolic extracts produced by maceration and homogenizer aided extraction showed glucosidase inhibition (0.11–1.11 mmol ACAE/g). These findings showed the overall bioactivity of the different extracts of A. fasciculiflora and provided an overview of the combination of solvent type and extraction method that could yield bioactive profile and pharmacological properties of interest and hence, could be a useful reference for future studies on this species.

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Section: Introductionmentioning

confidence: 99%

Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of Alcea fasciculiflora from Turkey?

et al. 2022

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“…Alcea genus belongs to Malvaceae family, and this genus is represented by 85 taxa in the world and 21 taxa in the Flora of Turkey (15,16). Alcea dissecta is a perennial plant and mainly grows in calcareous fields and roadside areas in the eastern parts of Anatolia, North West Iraq, and Palestine (17). The Malvaceae family contains high amounts of polyphenol compounds, known as chemotaxonomic markers.…”

Section: Introductionmentioning

confidence: 99%

In vitro Biological Activities of Different Extracts from Alcea dissecta

Taşkın

KAHVECİOĞLU

Türkoğlu

et al. 2022

Clinical and Experimental Health Sciences

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Objective: Alcea genus belongs to Malvaceae family and this genus is represented by 85 taxa in the world and 21 taxa in the Flora of Turkey. The flowers of Alcea genus contain plenty of mucilage and are used for the treatment of respiratory diseases such as asthma and cough. Alcea dissecta is known as 'Govik, Hiro, Hero' in Turkey, and the flowers and leaves of this species have been used in the treatment of asthma, injury, colds, and gastrointestinal diseases in Turkey. To the best of our knowledge, there is no report on the effect of extraction methods on the biological activity of this plant. In addition, although this species is being used as a medical plant, there is no study of the antioxidant, antiurease, esterase, and anticholinesterase activity of the plant. Therefore, the aim of this study was to evaluate in vitro antioxidant, anti-urease, esterase, anticholinesterase activities of Alcea dissecta using a variety of extracts. Methods:The antioxidant activities of different extracts were examined by DPPH, ABTS, FRAP, and CUPRAC methods. The total phenolic compounds contained in the extracts were determined using the Folin-Ciocalteu reagent (FCR) method. Anti-urease and anticholinesterase activities of different extracts were evaluated by indophenol and Ellman methods respectively. In addition, esterase activities of plant extracts were determined. Results:In the present study, ethanol:water (1:1, v/v) and chloroform extracts obtained maceration method showed stronger DPPH and ABTS radical scavenging activity than other extracts. The chloroform extract obtained Soxhlet method was found to have higher FRAP and CUPRAC values than other extracts. It was also found that the ethanol extract obtained maceration method showed the most potent anti-urease and anticholinesterase activity. According to the results, the strongest inhibitory effect on both hCA I and II isoenzymes was shown by the petroleum ether extract obtained Soxhlet method. Conclusion:As a result, it was determined that different plant extracts have antioxidant, anti-urease, esterase, anticholinesterase activities. In addition, the data obtained from this study will shed light on future research on the biological activities of this species.

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“…In Turkey, it is commonly known as ''Gülhatmi'' and distributed in Artvin, Elazig, Erzincan, Erzurum, Tunceli provinces (Akan et al, 2015;Konczak et al, 2014;Korkmaz et al, 2014;TÜBĠVES). Although, Alcea calvertii thought to be Anatolia-endemic herb (Beğen and Yüksel, 2018;Uzunhisarcıklı and Vural, 2012) the studies in the other countries disproved that (Korkmaz et al, 2014;2014b).…”

Section: Introductionmentioning

confidence: 99%

Alcea calvertii'nin Biyolojik Aktivitelerinin İncelenmesi

Asadi

Kanbolat

Ergene

et al. 2022

Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi

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Herbs are widely used in the treatment of diseases as colds, infections, and cancer. In this work, we evaluate Alcea calvertii, which is a perennial herbaceous plant belonging to the Malvaceae family. It spreads in Anatolia and Mediterranean region and has important uses in terms of ethnobotany. In this study, it was aimed to evaluate the cytotoxic potentials and to investigate the antioxidant activities of methanol, water, chloroform, and ethyl acetate extracts of the aerial parts of Alcea calvertii. For that, the antioxidant activity of Alcea calvertii was determined by four different methods [total phenolic content (TPC), ferric reducing antioxidant power (FRAP), copper reducing antioxidant capacity (CUPRAC) and 2,2-diphenylpicrylhydrazil (DPPH) radical scavenging activity. The cytotoxicity potential of extracts was assessed in the human lung cancer cell line (A549) by MTT assay. It was observed that the highest antioxidant activity was in the methanol extract and the antioxidant activity increased with increasing extract concentration; The TPC values were between 62.5 -414.6 GAE µg mL -1 , the FRAP values were between 115.7 -1321.4 µM Trolox equivalent g -1 , CUPRAC values were between 177.1 -1321.4 µM Trolox equivalent g -1 , and IC50 values in DPPH determination were between 0.0089 -3.5370 mg mL -1 . The extracts caused cytotoxicity in a concentration dependent manner, the IC50 values were calculated to be between 36.8 -62.64 µg mL -1 . It is concluded that Alcea calvertii could be an important herb in developing new drugs.

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The taxonomic revision of Alcea and Althaea (Malvaceae) in Turkey

Cited by 12 publications

References 0 publications

Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of Alcea fasciculiflora from Turkey?

Which Extraction Solvents and Methods Are More Effective in Terms of Chemical Composition and Biological Activity of Alcea fasciculiflora from Turkey?

In vitro Biological Activities of Different Extracts from Alcea dissecta

Alcea calvertii'nin Biyolojik Aktivitelerinin İncelenmesi

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