The Sunlight Factor in Aging and Skin Cancer

Howell, J. B.

doi:10.1001/archderm.1960.01580060019003

Cited by 25 publications

(1 citation statement)

References 7 publications

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“…This assumption is based on the well known fact that the incidence rate of epitheliomas in fair-skinned subjects, in whom tanning does not readily occur, is higher than in subjects with a swartliy or black skin. This circumstance may be accounted for by an inabihty of melanin in fair-skinned people to absorb ultra-violet radiation and prevent its penetration into the skin (Mackie and McGovern, 1958;Lodnoz, 1959;Everett et al, 1960;Howell, 1960). However, on this assumption it is hard to understand why epitheliomas also occur in dark-skinned subjects, and conversely, why fair-skinned subjects who have been exposed to sunlight for years do not necessarily develoi) epitheliomas.…”

Section: Discussionmentioning

confidence: 99%

Altered Skin Reflectance in Patients With Epithelioma

Băluş¹,

Ciureş²,

Harap³

et al. 1968

Br J Dermatol

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SUMMARY. The reflectance of monochromatic light projected on to 2 skin areas, one chronically exposed to sunlight (forehead) and the other shielded from it by clothing (buttock) has been determined in a group of patients suffering from epitheliomas of the face and in a control group. The forehead/buttock reflectance ratio (c) was computed and found to be significantly increased within the wavelength range from 480 578 nm in subjects with epitheliomas. These results reveal the existence in the skin of these patients of some as yet unknown morphological changes. The occurrence of these changes may be the expression of a predisposition to cancer related to an altered absorption of sunlight by the skin of patients with epitheliomas.

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Section: Discussionmentioning

confidence: 99%

Altered Skin Reflectance in Patients With Epithelioma

Băluş¹,

Ciureş²,

Harap³

et al. 1968

Br J Dermatol

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Ultraviolet Phototherapy and Photochemotherapy of Acne Vulgaris

Mills¹

1978

Arch Dermatol

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Aggressive-Growth Basal Cell Carcinoma in Young Adults

et al. 1991

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Aggressive-growth basal cell carcinoma (AG-BCC) defines a group of basal cell cancers that are histologically and clinically aggressive. This group includes morpheaform, infiltrating, and recurrent BCCs. Because of the clinical observation that the incidence of AG-BCC may be increased in patients under 35 years of age, compared with those older, we performed a retrospective study. We reviewed the pathologic findings of 3381 patients diagnosed with BCC, including 102 patients with BCC referred for Mohs surgery to determine whether AG-BCC occurs with increased frequency in patients younger than than 35 years of age. Among patients under 35 years of age, 38% of women had AG-BCC compared with 9% of women in the older age group. Similarly, 25% of men under 35 years of age had AG-BCC compared with 11% among men in the older age group. Aggressive-growth BCC is more frequently noted in patients under 35 years of age than in those older. Failure to diagnose this type of BCC, which may be clinically subtle, may lead to incomplete or inadequate treatment. Because of the tendency of these tumors to recur, greater long-term morbidity may result.

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The Sunlight Factor in Aging and Skin Cancer

Cited by 25 publications

References 7 publications

Altered Skin Reflectance in Patients With Epithelioma

Altered Skin Reflectance in Patients With Epithelioma

Ultraviolet Phototherapy and Photochemotherapy of Acne Vulgaris

Aggressive-Growth Basal Cell Carcinoma in Young Adults

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