The Study of Prevalence of Helicobacter Pylori in Patients with Acne Rosacea

Bhattarai, Shristi; Agrawal, Sudha; Rijal, Arpana; Majhi, S; Pradhan, Bickram; Dhakal, Sushil

doi:10.3126/kumj.v10i4.10995

Cited by 16 publications

(18 citation statements)

References 23 publications

(26 reference statements)

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“…Fourteen studies were included in the final analysis, including a total of 928 rosacea patients and 1527 controls. All studies were published between 1998 and 2015; six were from Southern Europe, two from Northern Europe, two from the United States, and one study from Egypt, Nepal, Korea and Brazil, respectively. Seven of the included studies also examined the effect of therapy on rosacea‐related skin symptoms.…”

Section: Resultsmentioning

confidence: 99%

Rosacea is associated with Helicobacter pylori: a systematic review and meta‐analysis

Jørgensen

Egeberg

Gideonsson

et al. 2017

Acad Dermatol Venereol

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Section: Resultsmentioning

confidence: 99%

Rosacea is associated with Helicobacter pylori: a systematic review and meta‐analysis

Jørgensen

Egeberg

Gideonsson

et al. 2017

Acad Dermatol Venereol

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“…[10][11][12][13][14] The role of Helicobacter pylori-related gastritis in the pathogenesis of rosacea has also been a subject of controversy. Diverse prevalence of H. pylori infection has been reported among rosacea patients, [15][16][17][18][19][20][21] ranging 0-100%. Some studies have suggested that rosacea could be considered as an extra-gastric symptom of H. pylori infection or reported improved rosacea clinical course post-H. pylori eradication, 22,23 while others concluded no significant relationship between H. pylori infection and rosacea.…”

Section: Introductionmentioning

confidence: 99%

Effects of Helicobacter pylori treatment on rosacea: A single‐arm clinical trial study

Saleh

Naghavi-Behzad

Herizchi

et al. 2017

The Journal of Dermatology

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Rosacea is a chronic dermatological disease. Helicobacter pylori has been discussed as one of its causative factors. In this clinical trial study, we attempted to evaluate the effect of H. pylori standard eradication protocol on the rosacea clinical course. In this single-arm clinical trial, patients ascertained to have H. pylori infection based on serological studies were assessed to examine existence of rosacea. Patients with concurrent rosacea and H. pylori infection were included in the study and underwent standard H. pylori eradication therapy. Rosacea was evaluated using the Duluth rosacea grading score at the beginning, 2 months later and at the end of the trial (day 180). Of 872 patients positive for H. pylori, 167 patients (19.15%) manifested the clinical features of rosacea. The patients with concurrent rosacea were younger (P < 0.001) and with a female sex predominance (P = 0.03) when compared with rosacea-free patients. Of 167 patients, 150 received H. pylori eradication therapy, demonstrating a 92% (138/150) cure rate. The rosacea Duluth score grading on day 0, 60 and 180 among 138 patients significantly decreased in most of the criteria except for telangiectasias (P = 0.712), phymatous changes (P = 0.535) and the existence of peripheral involvement (P = 0.431). The present study concluded that H. pylori eradication leads to improvement of rosacea.

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“…Other authors suggest a causal relationship between the two disorders, based on the RS clinical improvement after HP treatment (2,3,4,5) and the high incidence of this microorganism in RS patients (6,7). Improvment in the symptomatology of the disease noticed after the treatment of HP infection is supported by several studies, while other authors consider that this treatment and RS evolution are not connected (8,9).…”

Section: Results Resultsmentioning

confidence: 95%

Rosacea and its comorbidities

Merticariu¹,

Marinescu²,

Giurcăneanu³

2016

JTMR

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Objectives: Rosacea is currently defined as an inflammatory cutaneous disease without systemic echoes. The objective of our paper is to review the published articles to confirm our belief that rosacea is associated to or can predispose to various diseases, mainly inflammatory diseases. Material and methods:Review all the papers published in the last two decades in PubMed, Google Academic and Medscape databases, linking rosacea and various disorders of the body systems. Results: We found that rosacea is associated to several illnesses of major systems (gastrointestinal, cardiovascular, respiratory) and that there are also links between rosacea and immune system disorders and psychiatric diseases. Rosacea clinical course can be influenced by various drugs prescribed for the previous mentioned diseases. Conclusions: Rosacea should no longer be considered a localized cutaneous condition but rather a complex pathology with systemic reverberation. Patients suffering of severe forms of rosacea for a long period of time should have a careful evaluation of body systems.

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The Study of Prevalence of Helicobacter Pylori in Patients with Acne Rosacea

Abstract: Background

Cited by 16 publications

References 23 publications

Rosacea is associated with Helicobacter pylori: a systematic review and meta‐analysis

Rosacea is associated with Helicobacter pylori: a systematic review and meta‐analysis

Effects of Helicobacter pylori treatment on rosacea: A single‐arm clinical trial study

Rosacea and its comorbidities

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