The study of kinetics and thermodynamics of selected pharmaceuticals and personal care products on agriculture soil

Abstract

KEYWORDSPollution of the aquatic environment by human and veterinary waste pharmaceuticals is an increasing area of concern but little is known about their ecotoxicological effects on wildlife. In this study, three pharmaceuticals were selected (ibuprofen, amoxicillin and caffeine) as examples that are released in the environment. All of them are marketed in the Palestinian market (Pharmacies), private clinics and hospitals. The adsorption of the selected pharmaceuticals was examined by batch sorption experiments onto agriculture soil. Pharmaceuticals adsorption kinetics followed the pseudo-second-order adsorption model. Adsorption isotherms were best fitted by the Freundlich isotherm model. The "n" parameters were higher than 1 and the Kf values for all of them were less than 1. High removal rates of amoxicillin and ibuprofen were achieved in acidic media (pH = 1-4) and reached more than 88% Except for the caffeine increased at higher pH and reached more than 92%. The thermodynamics parameters showed that the adsorption process on soil was spontaneous and exothermic. Soil Slurries Diffusion Isotherm Adsorption Pharmaceuticals

Synthesis, characterization and comparative study the antibacterial activities of some imine-amoxicillin derivatives

“…On the other hand, when we show the results of activity against Escherichia coli, Figure 4, we observed some important notes: the first that all compounds (1)(2)(3)(4)(5) in all concentrations have good activity against this bacteria and this inhibition increases with increasing the concentration of compounds. The second is the compound 5 has good activity compared to others.…”

Synthesis, characterization and comparative study the antibacterial activities of some imine-amoxicillin derivatives

“…On the other hand, when we show the results of activity against Escherichia coli, Figure 4, we observed some important notes: the first that all compounds (1)(2)(3)(4)(5) in all concentrations have good activity against this bacteria and this inhibition increases with increasing the concentration of compounds. The second is the compound 5 has good activity compared to others.…”

Composition and structure analyzer/featurizer for explainable machine-learning models to predict solid state structures

“…, 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, often associated with distortions and symmetry reductions 57 or simple atomic mixing ( e.g. , site defects).…”

“…However, the weighted approach might not be ideal for classication in cases where a certain subclass of compounds is studied with nearly identical ratios of elements (i.e., 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, oen associated with distortions and symmetry reductions 57 or simple atomic mixing (e.g., site defects). 58 Atomic mixing in a compound, sometimes could be detected from the composition.…”

Composition and structure analyzer/featurizer for explainable machine-learning models to predict solid state structures

“…However, the weighted approach might not be ideal for classification in cases where a certain subclass of compounds is studied with nearly identical ratios of elements (i.e., 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, often associated with distortions and symmetry reductions 57 or simple atomic mixing (e.g., site defects). 58 Atomic mixing in a compound could sometimes be detected from the composition.…”

Synthesis, characterization and comparative study the antibacterial activities of some imine-amoxicillin derivatives

“…On the other hand, when we show the results of activity against Escherichia coli, Figure 4, we observed some important notes: the first that all compounds (1)(2)(3)(4)(5) in all concentrations have good activity against this bacteria and this inhibition increases with increasing the concentration of compounds. The second is the compound 5 has good activity compared to others.…”

Composition and structure analyzer/featurizer for explainable machine-learning models to predict solid state structures

“…, 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, often associated with distortions and symmetry reductions 57 or simple atomic mixing ( e.g. , site defects).…”

“…However, the weighted approach might not be ideal for classication in cases where a certain subclass of compounds is studied with nearly identical ratios of elements (i.e., 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, oen associated with distortions and symmetry reductions 57 or simple atomic mixing (e.g., site defects). 58 Atomic mixing in a compound, sometimes could be detected from the composition.…”

Composition and structure analyzer/featurizer for explainable machine-learning models to predict solid state structures

“…However, the weighted approach might not be ideal for classification in cases where a certain subclass of compounds is studied with nearly identical ratios of elements (i.e., 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, often associated with distortions and symmetry reductions 57 or simple atomic mixing (e.g., site defects). 58 Atomic mixing in a compound could sometimes be detected from the composition.…”

Synthesis, characterization and comparative study the antibacterial activities of some imine-amoxicillin derivatives

“…On the other hand, when we show the results of activity against Escherichia coli, Figure 4, we observed some important notes: the first that all compounds (1)(2)(3)(4)(5) in all concentrations have good activity against this bacteria and this inhibition increases with increasing the concentration of compounds. The second is the compound 5 has good activity compared to others.…”

Composition and structure analyzer/featurizer for explainable machine-learning models to predict solid state structures

“…, 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, often associated with distortions and symmetry reductions 57 or simple atomic mixing ( e.g. , site defects).…”

“…However, the weighted approach might not be ideal for classication in cases where a certain subclass of compounds is studied with nearly identical ratios of elements (i.e., 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, oen associated with distortions and symmetry reductions 57 or simple atomic mixing (e.g., site defects). 58 Atomic mixing in a compound, sometimes could be detected from the composition.…”

Composition and structure analyzer/featurizer for explainable machine-learning models to predict solid state structures

“…However, the weighted approach might not be ideal for classification in cases where a certain subclass of compounds is studied with nearly identical ratios of elements (i.e., 1 : 1 vs. 49 : 51). 56 Index ratios can indirectly relate to more structural information, often associated with distortions and symmetry reductions 57 or simple atomic mixing (e.g., site defects). 58 Atomic mixing in a compound could sometimes be detected from the composition.…”