The straightforward synthesis of N-coordinated ruthenium 4-aryl-1,2,3-triazolato complexes by [3 + 2] cycloaddition reactions of a ruthenium azido complex with terminal phenylacetylenes and non-covalent aromatic interactions in structures

Abstract

The first example of synthesis of N-coordinated ruthenium 4-aryl-1,2,3-triazolato complexes by [3 + 2] cycloaddition reactions of a ruthenium azido complex with a series of terminal phenylacetylenes.

Synthesis of aryl‐functionalized, 1,5‐disubstituted 1,2,3‐triazoles and derivatives by arylation of zwitterionic ruthenium triazolato complexes

“…These weak noncovalent interactions undoubtedly provide supports for stabilizing the whole crystal structure. The aromatic interactions, which are a variety of weak hydrogen bond, are observed in a huge number of organic and organometallic compounds [31,32] and biomolecules [18] such as proteins, nucleic acids and which are believed to play an crucial role in molecular assemblies [33] and in scaffolding in DNA and RNA binding. [18] The cytotoxic activity of a variety of anticancer drugs have been confirmed to result from their aromatic interactions with DNA/biomolecular targets, thus influencing different cellular mechanisms.…”