The significance of certain epidemiological variants in the genesis of juvenile insulin-dependent diabetes mellitus - The need for a global program of co-operation.

Abstract

Published data from literature show a two-to four-fold increase in the incidence of JIDDM, in the Western hemisphere over the past decade (5% to 10-20%). WHO Expert Committee Technical Report Series No. 646 (1980) gives the risk of development of diabetes in the first two decades of life, in the sub-populations of Europe and North America, as 0.1% to 0.3%. In Japan, it is stated to be less than 0.02% ; in Tamil Nadu, India, we have calculated the risk to be less than 0.01%. The incidence of JIDDM amongst diabetics in urban Southern India has remained low and static in the last decade ; 0.8% and 0.84% in 1973 and 1981 respectively. This is so, despite the fact that infant and perinatal mortality rates over the past two decades have registered a sharp decline in our area. Childhood diabetes and its complications have not shown an uptrend in hospital admissions or infant mortality analysis. It is speculative that our ethnic group is lacks the genetic factor, Bf F, (which is strongly linked with HLA B,a and IDDM) and the increased association of S,. It remains to be elucidated whether the increased susceptibility to JIDDM of Caucasian children may be associated with a genetic factor or some other exogenous factor, Such as a nutritional factor or virus infection. A plea is made to exchange groups of diabetic children and study the "behavior" of their diabetes under different environments.

Fasting C-Peptide Response, and Its Clinical Impact in Type I Diabetics to a Novel Metaphysical Energy Healing Therapy—Preliminary Experience and Observations

“…Lack of access to, and the high cost of, insulin and other supplies, limited health professional expertise concerning childhood diabetes, lack of diabetes education, geographic isolation and extreme poverty can result in very poor outcomes-starting with frequent misdiagnosis at disease onset so the child dies untreated; then a high risk of early death from hypoglycaemia or ketoacidosis; and for those who survive, very poor blood glucose control. Such sustained poor control leads to impaired quality of life and develop severe complications (such as loss of vision, end-stage renal failure and severe neuropathy) in their 20s or even earlier [8]. But with the advent of this new modality of treatment (DAMM Therapy) the cost of treatment will be greatly reduced.…”

“…According to statistics gathered from the survey the risk of JIDDM to be <0.01%. And the authors have suggested that this figure may rise to as much as 0.02% or 0.04%, depending upon the regional variations in a vast multifaceted country like India [8].…”