volume 8, issue 2, P291-303 2016
DOI: 10.18632/aging.100893
View full text
|
Sign up to set email alerts
|
Share

Abstract: Abstract:In spite of great efforts, the mechanisms for postovulatory oocyte aging are not fully understood. Although our previous work showed that the FasL/Fas signaling facilitated oocyte aging, the intra-oocyte signaling pathways are unknown. Furthermore, the mechanisms by which oxidative stress facilitates oocyte aging and the causal relationship between Ca 2+ rises and caspase-3 activation and between the cell cycle and apoptosis during oocyte aging need detailed investigations. Our aim was to address the…

Expand abstract