The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004

Mandelzweig, Lori; Battler, A; Boyko, Valentina; Bueno, Héctor; Danchin, Nicolás; Filippatos, Gerasimos; Gitt, Anselm K.; Hasdai, David; Hasin, Yonathan; Marrugat, Jaume; Werf, Frans Van de; Wallentin, Lars; Behar, Shlomo

doi:10.1093/eurheartj/ehl196

Cited by 498 publications

(347 citation statements)

References 13 publications

Supporting

Mentioning

247

Contrasting

Unclassified

Order By: Relevance

“…11,12 This difference in age at presentation may be due to the higher prevalence of CAD risk factors in our study. As in a previous study, 2 the proportion of women increased with increasing age and the risk factor pattern also varied with age.…”

Section: Discussionmentioning

confidence: 69%

Age and clinical outcomes in patients presenting with acute coronary syndromes

Ahmed

AlHabib

El‐Menyar

et al. 2013

Journal of Cardiovascular Disease Research

View full text Add to dashboard Cite

a b s t r a c tContext: Elderly patients have more cardiovascular risk factors and a greater burden of ischemic disease than younger patients. Aims: To examine the impact of age on clinical presentation and outcomes in patients presenting with acute coronary syndrome (ACS). Methods and material: Collected data from the 2nd Gulf Registry of Acute Coronary Events (Gulf RACE-2), which is a prospective multicenter study from six adjacent Arab Middle Eastern Gulf countries. Patients were divided into 3 groups according to their age: 50 years, 51e70 years and >70 years and their clinical characteristics and outcomes were analyzed. Mortality was assessed at one and 12 months. Statistical analysis used: One-way ANOVA test for continuous variables, Pearson chi-square (X 2 ) test for categorical variables and multivariate logistic regression analysis for predictors were performed. Results: Among 7930 consecutive ACS patients; 2755 (35%) were 50 years, 4110 (52%) were 51e70 years and 1065 (13%) >70 years old. The proportion of women increased with increasing age (13% among patients 50 years to 31% among patients > 70 years). The risk factor pattern varied with age; younger patients were more often obese, smokers and had a positive family history of CAD, whereas older patients more likely to have diabetes mellitus, hypertension, and dyslipidemia. Advancing age was associated with under-treatment evidence-based therapies. Multivariate logistic regression analysis after adjusting for relevant covariates showed that old age was independent predictors for re-ischemia (OR 1.29; 95% CI 1.03e1.60), heart failure (OR 2.8; 95% CI 2.17e3.52) and major bleeding (OR 4.02; 95% CI 1.37 e11.77) and in-hospital mortality (age 51e70: OR 2.67; 95% CI 1.86e3.85, and age >70: OR 4.71; 95% CI 3.11e7.14). Conclusion: Despite being higher risk group, elderly are less likely to receive evidence-based therapies and had worse outcomes. Guidelines adherence is highly recommended in elderly.

show abstract

Section: Discussionmentioning

confidence: 69%

Age and clinical outcomes in patients presenting with acute coronary syndromes

Ahmed

AlHabib

El‐Menyar

et al. 2013

Journal of Cardiovascular Disease Research

View full text Add to dashboard Cite

show abstract

“…In-hospital mortality of ST elevation myocardial infarction (STEMI) patients observed in Europe ranges between 6% and 14% [1]. 12% of patients die within six months after infarction [2].…”

Section: What Determines the Risk For Stemi Patients?mentioning

confidence: 99%

Risk assessment in patients with ST elevation myocardial infarction treated with primary percutaneous coronary angioplasty. Does reduced duration of hospital stay affect the prognosis?

Dębiński¹,

Kondys

2017

Kardiol Pol

View full text Add to dashboard Cite

“…However, long-term secondary stroke prevention in Germany has revealed better findings, especially with regard to antithrombotic medications (Hamann et al 2003). Even though therapeutic guideline implementation has improved over the past years (Mandelzweig et al 2006;Wienbergen et al 2001), only few studies in Germany have examined whether treatment recommendations after hospital discharge were according to current guidelines and to what extent these recommendations were realised in subsequent primary care (Zeymer et al 2007). The goal of this study was to compare treatment recommendations for secondary pharmacological prevention of ACS and stroke after hospital discharge with current guidelines and to examine changes in medication between initial hospitalisation and continued medical care.…”

Section: Introductionmentioning

confidence: 99%

Changes in secondary pharmacological prevention of acute coronary syndromes and stroke after hospital discharge: a 6-month follow-up study of German primary care patients

et al. 2008

View full text Add to dashboard Cite

Aim: This study examined modifications in secondary preventive medication between the time of hospital discharge (HD) and during a 6-month follow-up treatment of outpatients with acute coronary syndromes (ACS) and stroke. Subjects and methods: During a 6-month period, a health diary was completed on a weekly basis by 98 patients who were initially hospitalised with ACS and 29 patients with strokes in the Cologne area (Germany). Changes in medication between the time of HD and follow-up treatment (weeks 2, 12, and 24) were recorded. Results: On average, patients with ACS took six medications, whereas patients with stroke took five medications per day. ACS patients received beta-blockers (96%), lipid-lowering agents (80%), and angiotensin-converting enzyme (ACE) inhibitors (64%) at HD, and no changes in medication were made during follow-up treatment. However, there was a significant decrease in prescriptions of clopidogrel among ACS patients within 6 months, and about 13% of ACS patients did not receive an antiplatelet agent at any time. Stroke patients received beta-blockers (50%), lipid-lowering agents (67%), and antiplatelet agents, such as acetylsalicylic acid (57%) or clopidogrel (27%), at the time of HD, and no significant changes in medication were instituted during follow-up treatment. Conclusion: Treatment of ACS patients with the combination of acetylsalicylic acid and clopidogrel was insufficient, although it has been shown that this combination is highly effective in secondary prevention of ACS. Besides medical reasons, the cost-containment restrictions (“medication budget”) for German physicians might explain the observed failure of guideline-oriented medication. Furthermore, no changes in medications occurred regarding blood-pressure- and lipid-lowering agents

show abstract

The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004

Abstract: Data from EHS-ACS-II suggest an increase in adherence to guidelines for treatment of ACS in comparison with EHS-ACS-I.

Cited by 498 publications

References 13 publications

Age and clinical outcomes in patients presenting with acute coronary syndromes

Age and clinical outcomes in patients presenting with acute coronary syndromes

Risk assessment in patients with ST elevation myocardial infarction treated with primary percutaneous coronary angioplasty. Does reduced duration of hospital stay affect the prognosis?

Changes in secondary pharmacological prevention of acute coronary syndromes and stroke after hospital discharge: a 6-month follow-up study of German primary care patients

Contact Info

Product

Resources

About