The Role of the Oxidative Stress Markers in Endotelial Dysfunction at Cardiovascular Disease Patients

Abstract

Although oxidative stress itself is directly associated with the occurrence of atherosclerosis, and together with endothelial dysfunction is a marker of atherosclerotic risk, none of these two markers were directly correlated with the presence of atherosclerosis. This study investigated the correlation between oxidative stress and endothelial dysfunction in people with cardiovascular disease. Furthermore, another objective of this paper is the direct study of the effect of a compound with antioxidant properties, selenium, on a model of endothelial dysfunction induced on human vascular fragments.