The role of mutagenicity testing in the ecotoxicological evaluation of industrial discharges into the aquatic environment

Potential genotoxicity of wastewater‐contaminated pore waters with comparison to sediment toxicity and macrobenthic community composition*

“…Consequently, the wastewaters could not be considered, with one exception (Municipal Wastewater 1) the likely source of the mutagenic activity. This lack of a causal relationship contrasts the results reported for other industrial wastewaters and genotoxic assays (Rannug, 1980;de Raat et al, 1985;Møller et al, 1986;Bilawchuck et al, 1989;Houk, 1992;Wong et al, 1994;Rao et al, 1995;Legault et al, 1996).…”

Potential genotoxicity of wastewater‐contaminated pore waters with comparison to sediment toxicity and macrobenthic community composition*

“…Consequently, the wastewaters could not be considered, with one exception (Municipal Wastewater 1) the likely source of the mutagenic activity. This lack of a causal relationship contrasts the results reported for other industrial wastewaters and genotoxic assays (Rannug, 1980;de Raat et al, 1985;Møller et al, 1986;Bilawchuck et al, 1989;Houk, 1992;Wong et al, 1994;Rao et al, 1995;Legault et al, 1996).…”

Determination of Genotoxic Pollution of Some Hospital Wastewater with Salmonella Ames Test

“…In prospective studies, it is necessary to use this system as a method to monitor mutagenic genotoxic pollution in hospital wastewaters. These kinds of studies present applicability and importance of our method because of placing in the literature [19,[23][24][25].…”

Detecting genotoxic activity in industrial effluents using the SOS Chromotest microplate assay

“…In fact, effluents from inorganic and organic chemical plants, textile plants, pulp and paper mills, metallurgical plants, and petroleum refineries have been shown to contain genotoxic compounds, some of which have been identified as potent mutagens, teratogens, and carcinogens (Houk, 1992). Since it has been argued that genotoxic chemicals have no real "safe exposure level," their presence in the environment is certainly cause €or concern (Brandes et al, 1985;de Raat et al, 1985). Consequently, the inclusion of genotoxicity tests in ecotoxicological studies is fully warranted (de Raat et al, 1990;Costan et al, 1993; U.S. Environmental Protection Agency (EPA), 1991).…”

Potential genotoxicity of wastewater‐contaminated pore waters with comparison to sediment toxicity and macrobenthic community composition*

“…Consequently, the wastewaters could not be considered, with one exception (Municipal Wastewater 1) the likely source of the mutagenic activity. This lack of a causal relationship contrasts the results reported for other industrial wastewaters and genotoxic assays (Rannug, 1980;de Raat et al, 1985;Møller et al, 1986;Bilawchuck et al, 1989;Houk, 1992;Wong et al, 1994;Rao et al, 1995;Legault et al, 1996).…”

Determination of Genotoxic Pollution of Some Hospital Wastewater with Salmonella Ames Test

“…In prospective studies, it is necessary to use this system as a method to monitor mutagenic genotoxic pollution in hospital wastewaters. These kinds of studies present applicability and importance of our method because of placing in the literature [19,[23][24][25].…”

Detecting genotoxic activity in industrial effluents using the SOS Chromotest microplate assay

“…In fact, effluents from inorganic and organic chemical plants, textile plants, pulp and paper mills, metallurgical plants, and petroleum refineries have been shown to contain genotoxic compounds, some of which have been identified as potent mutagens, teratogens, and carcinogens (Houk, 1992). Since it has been argued that genotoxic chemicals have no real "safe exposure level," their presence in the environment is certainly cause €or concern (Brandes et al, 1985;de Raat et al, 1985). Consequently, the inclusion of genotoxicity tests in ecotoxicological studies is fully warranted (de Raat et al, 1990;Costan et al, 1993; U.S. Environmental Protection Agency (EPA), 1991).…”

Potential genotoxicity of wastewater‐contaminated pore waters with comparison to sediment toxicity and macrobenthic community composition*

“…Consequently, the wastewaters could not be considered, with one exception (Municipal Wastewater 1) the likely source of the mutagenic activity. This lack of a causal relationship contrasts the results reported for other industrial wastewaters and genotoxic assays (Rannug, 1980;de Raat et al, 1985;Møller et al, 1986;Bilawchuck et al, 1989;Houk, 1992;Wong et al, 1994;Rao et al, 1995;Legault et al, 1996).…”

Determination of Genotoxic Pollution of Some Hospital Wastewater with Salmonella Ames Test

“…In prospective studies, it is necessary to use this system as a method to monitor mutagenic genotoxic pollution in hospital wastewaters. These kinds of studies present applicability and importance of our method because of placing in the literature [19,[23][24][25].…”

Detecting genotoxic activity in industrial effluents using the SOS Chromotest microplate assay

“…In fact, effluents from inorganic and organic chemical plants, textile plants, pulp and paper mills, metallurgical plants, and petroleum refineries have been shown to contain genotoxic compounds, some of which have been identified as potent mutagens, teratogens, and carcinogens (Houk, 1992). Since it has been argued that genotoxic chemicals have no real "safe exposure level," their presence in the environment is certainly cause €or concern (Brandes et al, 1985;de Raat et al, 1985). Consequently, the inclusion of genotoxicity tests in ecotoxicological studies is fully warranted (de Raat et al, 1990;Costan et al, 1993; U.S. Environmental Protection Agency (EPA), 1991).…”