volume 9, issue 10, P1031-1042 2002
DOI: 10.1038/sj.cdd.4401088
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## Abstract:Mitochondria arelife-essential' organelles for the production of metabolic energy in the form of ATP. Paradoxically mitochondria also play a key role in controlling the pathways that lead to cell death. This latter role of mitochondria is more than just aloss of function' resulting in an energy deficit but is an active process involving different mitochondrial proteins. Cytochrome c was the first characterised mitochondrial factor shown to be released from the mitochondrial intermembrane space and to be acti…

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