The Role of Microbiota Pattern in Anxiety and Stress Disorders—A Review of the State of Knowledge

Abstract

Interest in the human microbiome in terms of mental health has increased with the rise in psychiatric diseases and disorders. The digestive system, the immune system, the brain, and the autonomic nervous system can all suffer from long-term lack of sleep and relaxation brought on by stress. There is little doubt that stress affects the human intestinal microbiota’s health and encourages problems with its composition, according to scientific studies. Chronic stress exposure raises the risk of both physical and mental illnesses. Therefore, this review’s goal was to support the theory that diseases including anxiety and stress are influenced by microbiome patterns. A total of 8600 sources directly relevant to this study’s topic were chosen from the 236,808 records returned by the literature search, and those with the highest scientific value were then selected based on bibliometric impact factors, language, and year of publication. A total of 87 sources, the most recent scientific output, were finally used for the literature review’s final analysis. The small number of studies on the subject indicates that it is still a developing problem, according to the literature study.

Effects of Lactobacillus salivarius ssp. salicinius SA-03 Supplementation on Reversing Phthalate-Induced Asthma in Mice

“…This is due to the fact that Lactobacillus salivarius has the ability to induce the expression of receptors associated with the inhibition of pain responses, particularly OPRM1 in the gut [ 16 ]. In addition, it affects the brain–gut connection: by improving gut conditions resulting from antibiotic use or pathogen effects, it can indirectly improve cognitive function and reduce depressive states and anxiety [ 17 ]. A positive effect has also been noted on the cardiovascular system, and this is due to a reduction in cholesterol levels and blood pressure [ 18 ].…”