Archives of Otolaryngology - Head and Neck Surgery
 1996
DOI: 10.1001/archotol.1996.01890230047010
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The Role of Immunosuppression in the Long-term Survival of Tracheal Allografts

Pierre Delaere
1
,
Z Liu2,
Raf Sciot3
et al.
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Cited by 40 publications

(25 citation statements)
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“…If immunosuppressive agents for antibody control are incorporated, rabbit tracheal grafts would appear normal by tracheoscopy at 8 weeks after surgery. This phenomenon is similar to the healing mechanism associated with mucosal erosion in tracheal allografts without immunosuppression (12). We did not use specific immunosuppressants to control anti-rabbit antibodies.…”
Section: Discussionsupporting
confidence: 59%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…If immunosuppressive agents for antibody control are incorporated, rabbit tracheal grafts would appear normal by tracheoscopy at 8 weeks after surgery. This phenomenon is similar to the healing mechanism associated with mucosal erosion in tracheal allografts without immunosuppression (12). We did not use specific immunosuppressants to control anti-rabbit antibodies.…”
Section: Discussionsupporting
confidence: 59%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…The occurrence of necrosis and degeneration of tracheal cartilage in some area of the site of cutting may be due to ischemia that result from interruption of blood supply and innervations during removal tracheal segment. The developmental of epithelium of tracheal mucosa was not shown and this is regarded the major problems in tracheal prosthesis (39,40). New cartilage formation was showed in both groups these findings reveled the ability to use ear cartilage and scaffold calve pericardium to repair the tracheal defect.…”
Section: Discussionmentioning
confidence: 91%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Major shortcomings of this report are the statements that the trachea induces only weak antigenicity, while the mucosal lining and capillaries from the donor are highly antigenetic [32]. In addition, immunosuppressive therapy was not administered and the report did not document the viability of the allograft or the long-term outcome.…”
Section: History Of Tracheal Allotransplantationmentioning
confidence: 89%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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