The Role of Chlamydia pneumoniae in the Aetiology of Autoimmune Diseases
Basant K Puri,
Gary S Lee,
Armin Schwarzbach
Abstract:Introduction
The most prevalent chronic human autoimmune disorder worldwide is rheumatoid arthritis. Synovial samples from acute-phase patients are polymerase chain reaction-positive for
Chlamydia pneumoniae
(
C. pneumoniae
)
DNA and express chlamydial
hsp60
. Furthermore, anti-cyclic citrullinated peptide (anti-CCP) antibodies promote apoptosis of mature human Saos-2 osteoblasts via cell surface binding to citrullinated… Show more
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