The Role of ADC‐Based Thermometry in Measuring Brain Intraventricular Temperature in Children

Wagner, Matthias; Stern, Steven; Oshmyansky, Alexander; Huisman, Thierry A. G. M.; Poretti, Andrea

doi:10.1111/jon.12325

Cited by 3 publications

(3 citation statements)

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“…In contrast, the correlation between measured and calculated temperature using CSF ADC was poor (fetuses: r = 0.522, P = 0.122) and showed greater variance. This is probably due to the small volume of the ventricles and partial volume artifacts, 16 postmortem changes in the composition of the CSF, and additional blood degradation products. Blood degradation products in combination with partial volume artifacts will lower the ADC value, resulting in an incorrect lower temperature with this method of temperature calculation (as shown in Fig.…”

Section: Discussionmentioning

confidence: 99%

“…[13][14][15] In children and fetuses, this method is less reliable because of the small size of the ventricles and the effects of partial volume on ADC measurements. 16 In addition, the ADC measurements are affected by intraventricular blood products, which are common in PMMR. The vitreous body is less susceptible to postmortem changes than the CSF.…”

mentioning

confidence: 99%

“…The calculation of the temperature based on the ADC is commonly used in vivo to calculate the brain temperature 13–15 . In children and fetuses, this method is less reliable because of the small size of the ventricles and the effects of partial volume on ADC measurements 16 . In addition, the ADC measurements are affected by intraventricular blood products, which are common in PMMR.…”

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confidence: 99%

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Postmortem Fetal Temperature Estimation with Magnetic Resonance Imaging: Apparent Diffusion Coefficient Measurements in the Vitreous Body and Cerebrospinal Fluid

Tijssen

Hofman²,

Robben³

2022

Topics in Magnetic Resonance Imaging

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Objectives: Magnetic resonance imaging (MRI) is increasingly used in postmortem fetal imaging. Several factors influence the quality of MRI in this setting, such as small size, autolytic and maceration changes, and temperature. Knowing the fetal temperature at the time of scanning can improve the MRI interpretation. Temperature can be calculated using diffusion-weighted imaging with measurements of the apparent diffusion coefficient (ADC) in the cerebrospinal fluid (CSF). However, this is complicated by small ventricle size and hemorrhage and, therefore, may be unreliable in postmortem imaging. The current study evaluated the feasibility and reliability of using the ADC for temperature measurements of the vitreous body compared to that of CSF. Materials and Methods: Two lambs were scanned postmortem at five different time points over 28 hours. Furthermore, 10 stillborn fetuses were scanned once, at 4 to 62 hours after birth. The temperature was measured with a digital thermometer and calculated using the ADCs of the vitreous body (lambs and fetuses) and CSF (fetuses). Results: There was an excellent correlation between measured and calculated temperatures in vitreous bodies of lambs (r = 0.997, P < 0.001) and fetuses (r = 0.970, P < 0.001). The correlation between measured and calculated temperatures in the CSF was poor (r = 0.522, P = 0.122). Conclusion: The calculation of the temperature based on the ADC of the vitreous body is feasible and reliable for postmortem fetal imaging.

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Section: Discussionmentioning

confidence: 99%

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