The Role of 2,3‐diphosphoglycerate in Mediating Hemoglobin Function of Mammalian Red Cells *

Practicing Biochemistry without a License

“…Armed with a blow dart laced with a sedative and a syringe, he could be trusted to draw blood on any animal irrespective of size and ferocity with a virtual total absence of iatrogenic mishaps. This bonanza enabled us to extend the scope of our project to seventyone mammalian species covering fourteen orders (10). The results closely mimicked the earlier study mentioned above on domestic mammals.…”

Practicing Biochemistry without a License

“…Armed with a blow dart laced with a sedative and a syringe, he could be trusted to draw blood on any animal irrespective of size and ferocity with a virtual total absence of iatrogenic mishaps. This bonanza enabled us to extend the scope of our project to seventyone mammalian species covering fourteen orders (10). The results closely mimicked the earlier study mentioned above on domestic mammals.…”

High-altitude diving in river otters: coping with combined hypoxic stresses

“…Indeed, previous studies reported a higher 2,3-BPG concentration of 3.8mmoll -1 for North American river otters (Bunn et al, 1974). All other comparisons of serum chemistry, including total protein and hematology between high-altitude and sea-level otters were not significant at the 0.05 level (Table1).…”

Oxygenation properties and oxidation rates of mouse hemoglobins that differ in reactive cysteine content

“…This is an important finding because DPG is a much more potent allosteric effector than Cl − ions in the overwhelming majority of mammalian Hbs. The only documented exceptions include Hbs from select lineages of artiodactyls, carnivores, moles, and prosimian primates (Bunn, 1971; Taketa et al, 1971; Bunn et al, 1974; Campbell et al, 2010). …”

Practicing Biochemistry without a License

“…Armed with a blow dart laced with a sedative and a syringe, he could be trusted to draw blood on any animal irrespective of size and ferocity with a virtual total absence of iatrogenic mishaps. This bonanza enabled us to extend the scope of our project to seventyone mammalian species covering fourteen orders (10). The results closely mimicked the earlier study mentioned above on domestic mammals.…”

High-altitude diving in river otters: coping with combined hypoxic stresses

“…Indeed, previous studies reported a higher 2,3-BPG concentration of 3.8mmoll -1 for North American river otters (Bunn et al, 1974). All other comparisons of serum chemistry, including total protein and hematology between high-altitude and sea-level otters were not significant at the 0.05 level (Table1).…”

Oxygenation properties and oxidation rates of mouse hemoglobins that differ in reactive cysteine content

“…This is an important finding because DPG is a much more potent allosteric effector than Cl − ions in the overwhelming majority of mammalian Hbs. The only documented exceptions include Hbs from select lineages of artiodactyls, carnivores, moles, and prosimian primates (Bunn, 1971; Taketa et al, 1971; Bunn et al, 1974; Campbell et al, 2010). …”

Practicing Biochemistry without a License

“…Armed with a blow dart laced with a sedative and a syringe, he could be trusted to draw blood on any animal irrespective of size and ferocity with a virtual total absence of iatrogenic mishaps. This bonanza enabled us to extend the scope of our project to seventyone mammalian species covering fourteen orders (10). The results closely mimicked the earlier study mentioned above on domestic mammals.…”

High-altitude diving in river otters: coping with combined hypoxic stresses

“…Indeed, previous studies reported a higher 2,3-BPG concentration of 3.8mmoll -1 for North American river otters (Bunn et al, 1974). All other comparisons of serum chemistry, including total protein and hematology between high-altitude and sea-level otters were not significant at the 0.05 level (Table1).…”

Oxygenation properties and oxidation rates of mouse hemoglobins that differ in reactive cysteine content

“…This is an important finding because DPG is a much more potent allosteric effector than Cl − ions in the overwhelming majority of mammalian Hbs. The only documented exceptions include Hbs from select lineages of artiodactyls, carnivores, moles, and prosimian primates (Bunn, 1971; Taketa et al, 1971; Bunn et al, 1974; Campbell et al, 2010). …”