The Retinal Vasculature in Macular Degeneration

Modern Concepts of Senile Macular Degeneration*

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan ( 6 ) . Kornzweig et al (7) 248 showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) Zauberman et al (9) in 1970 studied predisciform and disciform macular degeneration with special attention to the arterioles surrounding the macula.…”

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan (6). Kornzweig et al (7) showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) concerned cystic degeneration in one eye and a hole in the macula in the other eye of the same patient; the adjacent pigment layer, lamina vitrea and choriocapillaris seemed normal in appearance under the light microscope (Figs.…”

Modern Concepts of Senile Macular Degeneration*

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan ( 6 ) . Kornzweig et al (7) 248 showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) Zauberman et al (9) in 1970 studied predisciform and disciform macular degeneration with special attention to the arterioles surrounding the macula.…”

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan (6). Kornzweig et al (7) showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) concerned cystic degeneration in one eye and a hole in the macula in the other eye of the same patient; the adjacent pigment layer, lamina vitrea and choriocapillaris seemed normal in appearance under the light microscope (Figs.…”

A New Vessel-Based Method to Estimate Automatically the Position of the Nonfunctional Fovea on Altered Retinography From Maculopathies

“…Finally, in the first step of our method, we only used images from young subjects to build our statistical representations of retina vessels. Given that retinal vessels exhibit changes with aging (most notably a decrease in density, especially around the fovea 43 , 44 ), future instances of VBFL should provide increased age range representations by including older adults’ images in the training set. Thanks to this individualized approach, the VBFL model would allow to apply an age-appropriate statistical representation map of vessel density and direction, taking into account potential changes in the density, direction or both of the vascular structure across the life span.…”

Retinal Vascularization Analysis on Optical Coherence Tomography Angiography before and after Intraretinal or Subretinal Fluid Resorption in Exudative Age-Related Macular Degeneration: A Pilot Study

“…Several studies have reported abnormal vascular changes in exudative or atrophic AMD [19,20]. This is not surprising as high blood pressure, smoking and obesity are risk factors of the disease [21].…”

Modern Concepts of Senile Macular Degeneration*

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan ( 6 ) . Kornzweig et al (7) 248 showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) Zauberman et al (9) in 1970 studied predisciform and disciform macular degeneration with special attention to the arterioles surrounding the macula.…”

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan (6). Kornzweig et al (7) showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) concerned cystic degeneration in one eye and a hole in the macula in the other eye of the same patient; the adjacent pigment layer, lamina vitrea and choriocapillaris seemed normal in appearance under the light microscope (Figs.…”

A New Vessel-Based Method to Estimate Automatically the Position of the Nonfunctional Fovea on Altered Retinography From Maculopathies

“…Finally, in the first step of our method, we only used images from young subjects to build our statistical representations of retina vessels. Given that retinal vessels exhibit changes with aging (most notably a decrease in density, especially around the fovea 43 , 44 ), future instances of VBFL should provide increased age range representations by including older adults’ images in the training set. Thanks to this individualized approach, the VBFL model would allow to apply an age-appropriate statistical representation map of vessel density and direction, taking into account potential changes in the density, direction or both of the vascular structure across the life span.…”

Retinal Vascularization Analysis on Optical Coherence Tomography Angiography before and after Intraretinal or Subretinal Fluid Resorption in Exudative Age-Related Macular Degeneration: A Pilot Study

“…Several studies have reported abnormal vascular changes in exudative or atrophic AMD [19,20]. This is not surprising as high blood pressure, smoking and obesity are risk factors of the disease [21].…”

Modern Concepts of Senile Macular Degeneration*

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan ( 6 ) . Kornzweig et al (7) 248 showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) Zauberman et al (9) in 1970 studied predisciform and disciform macular degeneration with special attention to the arterioles surrounding the macula.…”

“…Such a relationship was demonstrated in a study of the retinal circulation with use of the trypsin digestion technique of Kuwabara and Cogan (6). Kornzweig et al (7) showed that the number of atrophic capillaries around the fovea was markedly increased in patients with moderate and advanced senile macular degeneration. Another case report by Kornzweig and Feldstein (8) concerned cystic degeneration in one eye and a hole in the macula in the other eye of the same patient; the adjacent pigment layer, lamina vitrea and choriocapillaris seemed normal in appearance under the light microscope (Figs.…”

A New Vessel-Based Method to Estimate Automatically the Position of the Nonfunctional Fovea on Altered Retinography From Maculopathies

“…Finally, in the first step of our method, we only used images from young subjects to build our statistical representations of retina vessels. Given that retinal vessels exhibit changes with aging (most notably a decrease in density, especially around the fovea 43 , 44 ), future instances of VBFL should provide increased age range representations by including older adults’ images in the training set. Thanks to this individualized approach, the VBFL model would allow to apply an age-appropriate statistical representation map of vessel density and direction, taking into account potential changes in the density, direction or both of the vascular structure across the life span.…”

Retinal Vascularization Analysis on Optical Coherence Tomography Angiography before and after Intraretinal or Subretinal Fluid Resorption in Exudative Age-Related Macular Degeneration: A Pilot Study

“…Several studies have reported abnormal vascular changes in exudative or atrophic AMD [19,20]. This is not surprising as high blood pressure, smoking and obesity are risk factors of the disease [21].…”