The results of penicillin G administration on chronic unrestrained cats: Electrographic and behavioral observations

Rodin, Ervin Y.; Kitano, Hideto; Nagao, Bunichiro; Rodin, M.

doi:10.1016/0013-4694(77)90215-2

Cited by 22 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 shows a typical example of a paroxysmal arousal response (K complex with spikes, maximum overfrontal midline) in primarygeneralized epilepsy. 36 feel that this experimental model produces multifocal (cortical, cerebellar, thalamic) spike-wave activity rather than primary bilateral-synchronous discharges.…”

Section: The Role Of Arousing Stimuli In Lowered Vigilancementioning

confidence: 91%

Complexities of Primary Generalized Epilepsy

Niedermeyer

1981

Clinical Electroencephalography

View full text Add to dashboard Cite

Section: The Role Of Arousing Stimuli In Lowered Vigilancementioning

confidence: 91%

Complexities of Primary Generalized Epilepsy

Niedermeyer

1981

Clinical Electroencephalography

View full text Add to dashboard Cite

“…The term “generalized” has an additional disadvantage. It covers tonic–clonic convulsions, myoclonic jerks, and absence seizures, although they have different electrophysiologic origins (Rodin et al., 1977a). These considerations should be reflected in our thinking about an epileptic seizure, and they allow for a continuum between the two extremes rather than forcing a dichotomy.…”

Section: Seizure Definitionmentioning

confidence: 75%

Commentary: The Epilepsy Diathesis

Rodin¹

2009

Epilepsia

View full text Add to dashboard Cite

“…It was less pronounced and somewhat inconsistent inthalamic nuclei. Initial bursting was always in cortical structures rather than thalamic ones (12). In higher doses the animals developed focal onset tonic-clonic seizures rather than "primary" generalized ones.…”

Section: Ultrafast Datamentioning

confidence: 88%

Paper Recordings of Ultrafast Frequencies in Experimental Epilepsy

Rodin

2005

Clin EEG Neurosci

View full text Add to dashboard Cite

Digital EEG technology has facilitated the recording of fast activity above 50 Hz, but previous work carried out in this field is, commonly, no longer referred to in the literature. This paper presents a summary of our experience in experimental epilepsy when frequencies above 100 Hz were recorded. It was shown that conventional recordings (1-70 Hz) do not correlate with the onset of clinical seizures and can actually lead to misleading neurophysiologic conclusions. Ultrafast activity (100-1500 Hz), on the other hand, showed excellent correlation with clinical behavior and pointed to the low brainstem for the origin of nonfocal tonic-clonic seizures. In the animal analogue of absence seizures the cortex, including cingulate gyrus, thalamus, and cerebellum, showed greater involvement than other brain structures. Ultrafast activity has a very limited electrical field, and evoked responses remain restricted to the corresponding sensory pathways. Focal penicillin administration led not only to spike generation but also to associated ultrafast frequency bursts in that area. It appears likely that ultrafast burst activity may be a better marker for focal cortical epileptogenesis than spikes or sharp waves, which can be transmitted from a distance.

show abstract

The results of penicillin G administration on chronic unrestrained cats: Electrographic and behavioral observations

Cited by 22 publications

References 11 publications

Complexities of Primary Generalized Epilepsy

Complexities of Primary Generalized Epilepsy

Commentary: The Epilepsy Diathesis

Paper Recordings of Ultrafast Frequencies in Experimental Epilepsy

Contact Info

Product

Resources

About