The response of erythrocyte organic phosphate levels of active and hibernating ground squirrels (Spermophilus mexicanus) to isobaric hyperoxia

The Role of 2,3‐diphosphoglycerate in Mediating Hemoglobin Function of Mammalian Red Cells *

“…It may be of physiological significance that hibernating mam-rnals3l. 32 or those living at high altitude (FIGURE 3 and References 20 & 33)) tend to have low P,, values, indicative of increased affinity for oxygen. There are probably other environmental factors that could influence the oxygen loading and unloading properties of red cells from different species.…”

The Role of 2,3‐diphosphoglycerate in Mediating Hemoglobin Function of Mammalian Red Cells *

“…It may be of physiological significance that hibernating mam-rnals3l. 32 or those living at high altitude (FIGURE 3 and References 20 & 33)) tend to have low P,, values, indicative of increased affinity for oxygen. There are probably other environmental factors that could influence the oxygen loading and unloading properties of red cells from different species.…”

Studies on the Interaction of Organic Phosphates with Haemoglobin in an Amphibian (Bufo marinus), a Reptile (Trachydosaurus rugosus) and Man

“…The functional properties of haemoglobins from most classes of vertebrates have been shown to be modified by certain organic phosphates of the red blood cell cytoplasm* (Benesch et al 1968;Johnson and Tate 1969;Gillen and Riggs 1971;Wood 1971;Misson and Freeman 1972;Anderson et al 1973;Larkin 1973;Taketa and Nickerson 1973;Vandecasserie et al 1973;Geoghegan and Poluhowich 1974). The organic phosphates of the red blood cell cytoplasm so far shown to be modifiers of haemoglobin function are ADP, ATP, GTP, DPG (2,3-diphosphoglycerate), and myo-IP 5 (myo-inositol pentaphosphate).…”

The Role of 2,3‐diphosphoglycerate in Mediating Hemoglobin Function of Mammalian Red Cells *

“…It may be of physiological significance that hibernating mam-rnals3l. 32 or those living at high altitude (FIGURE 3 and References 20 & 33)) tend to have low P,, values, indicative of increased affinity for oxygen. There are probably other environmental factors that could influence the oxygen loading and unloading properties of red cells from different species.…”

Studies on the Interaction of Organic Phosphates with Haemoglobin in an Amphibian (Bufo marinus), a Reptile (Trachydosaurus rugosus) and Man

“…The functional properties of haemoglobins from most classes of vertebrates have been shown to be modified by certain organic phosphates of the red blood cell cytoplasm* (Benesch et al 1968;Johnson and Tate 1969;Gillen and Riggs 1971;Wood 1971;Misson and Freeman 1972;Anderson et al 1973;Larkin 1973;Taketa and Nickerson 1973;Vandecasserie et al 1973;Geoghegan and Poluhowich 1974). The organic phosphates of the red blood cell cytoplasm so far shown to be modifiers of haemoglobin function are ADP, ATP, GTP, DPG (2,3-diphosphoglycerate), and myo-IP 5 (myo-inositol pentaphosphate).…”

The Role of 2,3‐diphosphoglycerate in Mediating Hemoglobin Function of Mammalian Red Cells *

“…It may be of physiological significance that hibernating mam-rnals3l. 32 or those living at high altitude (FIGURE 3 and References 20 & 33)) tend to have low P,, values, indicative of increased affinity for oxygen. There are probably other environmental factors that could influence the oxygen loading and unloading properties of red cells from different species.…”

Studies on the Interaction of Organic Phosphates with Haemoglobin in an Amphibian (Bufo marinus), a Reptile (Trachydosaurus rugosus) and Man

“…The functional properties of haemoglobins from most classes of vertebrates have been shown to be modified by certain organic phosphates of the red blood cell cytoplasm* (Benesch et al 1968;Johnson and Tate 1969;Gillen and Riggs 1971;Wood 1971;Misson and Freeman 1972;Anderson et al 1973;Larkin 1973;Taketa and Nickerson 1973;Vandecasserie et al 1973;Geoghegan and Poluhowich 1974). The organic phosphates of the red blood cell cytoplasm so far shown to be modifiers of haemoglobin function are ADP, ATP, GTP, DPG (2,3-diphosphoglycerate), and myo-IP 5 (myo-inositol pentaphosphate).…”