The response characteristics of rat taste cells to four basic taste stimuli

Individual mouse taste cells respond to multiple chemical stimuli

“…Our results are consistent with those of previous electrophysiological studies showing multiple sensitivity of taste cells (Kimura & Beidler, 1961; Ozeki, 1971; Ozeki & Sato, 1972; Sato & Beidler, 1982, 1997; Tonosaki & Funakoshi, 1984; Gilbertson et al 2001). In our study, however, we found a generally lower incidence of responses to chemical stimuli.…”

Individual mouse taste cells respond to multiple chemical stimuli

“…Our results are consistent with those of previous electrophysiological studies showing multiple sensitivity of taste cells (Kimura & Beidler, 1961; Ozeki, 1971; Ozeki & Sato, 1972; Sato & Beidler, 1982, 1997; Tonosaki & Funakoshi, 1984; Gilbertson et al 2001). In our study, however, we found a generally lower incidence of responses to chemical stimuli.…”

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

“…While we do not rule out the possibility that taste cells receive input from other taste cells, our data show that BR Type III cells do not require neighboring input to respond to bitter, sweet and/or umami stimuli. Taken with these earlier studies (Caicedo et al, 2002, Gilbertson et al, 2001, Kimura & Beidler, 1961, Ozeki, 1971, Ozeki & Sato, 1972, Sato & Beidler, 1982, Sato & Beidler, 1997, Tomchik et al, 2007, Tonosaki & Funakoshi, 1984, Yoshida et al, 2009), our data support the idea that there are both selectively and broadly responsive cells in taste buds. In agreement with others (Tomchik et al, 2007, Yoshida et al, 2009), our data indicate that these broadly responsive cells are a subset of Type III taste cells and we have now shown that BR cells can independently respond to bitter, sweet and umami stimuli.…”

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

“…While we do not rule out the possibility that taste cells receive input from other taste cells, our data show that BR Type III cells do not require neighboring input to respond to bitter, sweet, and/ or umami stimuli. Taken with these earlier studies [30,31,[43][44][45][46][47][48][49][50], our data support the idea that there are both selectively and broadly responsive cells in taste buds. In agreement with others [30,31], our data indicate that these BR cells are a subset of Type III taste cells and we have now shown that BR cells can independently respond to bitter, sweet, and umami stimuli.…”

“…The idea of broadly tuned taste cells in mammals has been put forth by multiple labs, using a variety of approaches that utilized whole taste buds [43][44][45][46][47][48][49][50]. Maintaining the taste cells in the bud allowed for measurements in a more "native" environment and allowed stimuli to be apically applied to the cells.…”

Individual mouse taste cells respond to multiple chemical stimuli

“…Our results are consistent with those of previous electrophysiological studies showing multiple sensitivity of taste cells (Kimura & Beidler, 1961; Ozeki, 1971; Ozeki & Sato, 1972; Sato & Beidler, 1982, 1997; Tonosaki & Funakoshi, 1984; Gilbertson et al 2001). In our study, however, we found a generally lower incidence of responses to chemical stimuli.…”

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

“…While we do not rule out the possibility that taste cells receive input from other taste cells, our data show that BR Type III cells do not require neighboring input to respond to bitter, sweet and/or umami stimuli. Taken with these earlier studies (Caicedo et al, 2002, Gilbertson et al, 2001, Kimura & Beidler, 1961, Ozeki, 1971, Ozeki & Sato, 1972, Sato & Beidler, 1982, Sato & Beidler, 1997, Tomchik et al, 2007, Tonosaki & Funakoshi, 1984, Yoshida et al, 2009), our data support the idea that there are both selectively and broadly responsive cells in taste buds. In agreement with others (Tomchik et al, 2007, Yoshida et al, 2009), our data indicate that these broadly responsive cells are a subset of Type III taste cells and we have now shown that BR cells can independently respond to bitter, sweet and umami stimuli.…”

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

“…While we do not rule out the possibility that taste cells receive input from other taste cells, our data show that BR Type III cells do not require neighboring input to respond to bitter, sweet, and/ or umami stimuli. Taken with these earlier studies [30,31,[43][44][45][46][47][48][49][50], our data support the idea that there are both selectively and broadly responsive cells in taste buds. In agreement with others [30,31], our data indicate that these BR cells are a subset of Type III taste cells and we have now shown that BR cells can independently respond to bitter, sweet, and umami stimuli.…”

“…The idea of broadly tuned taste cells in mammals has been put forth by multiple labs, using a variety of approaches that utilized whole taste buds [43][44][45][46][47][48][49][50]. Maintaining the taste cells in the bud allowed for measurements in a more "native" environment and allowed stimuli to be apically applied to the cells.…”

Individual mouse taste cells respond to multiple chemical stimuli

“…Our results are consistent with those of previous electrophysiological studies showing multiple sensitivity of taste cells (Kimura & Beidler, 1961; Ozeki, 1971; Ozeki & Sato, 1972; Sato & Beidler, 1982, 1997; Tonosaki & Funakoshi, 1984; Gilbertson et al 2001). In our study, however, we found a generally lower incidence of responses to chemical stimuli.…”

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

“…While we do not rule out the possibility that taste cells receive input from other taste cells, our data show that BR Type III cells do not require neighboring input to respond to bitter, sweet and/or umami stimuli. Taken with these earlier studies (Caicedo et al, 2002, Gilbertson et al, 2001, Kimura & Beidler, 1961, Ozeki, 1971, Ozeki & Sato, 1972, Sato & Beidler, 1982, Sato & Beidler, 1997, Tomchik et al, 2007, Tonosaki & Funakoshi, 1984, Yoshida et al, 2009), our data support the idea that there are both selectively and broadly responsive cells in taste buds. In agreement with others (Tomchik et al, 2007, Yoshida et al, 2009), our data indicate that these broadly responsive cells are a subset of Type III taste cells and we have now shown that BR cells can independently respond to bitter, sweet and umami stimuli.…”

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

“…While we do not rule out the possibility that taste cells receive input from other taste cells, our data show that BR Type III cells do not require neighboring input to respond to bitter, sweet, and/ or umami stimuli. Taken with these earlier studies [30,31,[43][44][45][46][47][48][49][50], our data support the idea that there are both selectively and broadly responsive cells in taste buds. In agreement with others [30,31], our data indicate that these BR cells are a subset of Type III taste cells and we have now shown that BR cells can independently respond to bitter, sweet, and umami stimuli.…”

“…The idea of broadly tuned taste cells in mammals has been put forth by multiple labs, using a variety of approaches that utilized whole taste buds [43][44][45][46][47][48][49][50]. Maintaining the taste cells in the bud allowed for measurements in a more "native" environment and allowed stimuli to be apically applied to the cells.…”