The renal reabsorption of arginine, lysine and ornithine in the young cockerel (Gallusdomesticus)

Performance and Concentration of Amino Acids in Plasma and Urine of Young Pigs Fed Diets with Excesses of Either Arginine or Lysine

“…These data indicate that arginine and(or) ornithine concentrations reached levels high enough to surpass efficient renal reabsorption of these amino acids in pigs fed the diet containing 2.8% total arginine. This also agrees well with the concept that arginine and(or) ornithine inhibit the renal reabsorption of lysine, citrulline, cystine and histidine (Beyer et al, 1947;Kamin and Handler, 1951;Weber et al, 1961;Boorman, 1971;Boorman and Falconer, 1972;Christensen and Cullen, 1973). Amino acids excreted in the urine represented a small and insignificant percentage of the amino acids consumed.…”

Performance and Concentration of Amino Acids in Plasma and Urine of Young Pigs Fed Diets with Excesses of Either Arginine or Lysine

“…These data indicate that arginine and(or) ornithine concentrations reached levels high enough to surpass efficient renal reabsorption of these amino acids in pigs fed the diet containing 2.8% total arginine. This also agrees well with the concept that arginine and(or) ornithine inhibit the renal reabsorption of lysine, citrulline, cystine and histidine (Beyer et al, 1947;Kamin and Handler, 1951;Weber et al, 1961;Boorman, 1971;Boorman and Falconer, 1972;Christensen and Cullen, 1973). Amino acids excreted in the urine represented a small and insignificant percentage of the amino acids consumed.…”

Renal transport of lysine and arginine in cystinuria.

“…Since Pitts (1943) first reported the titration curve of glycine in dog, renal transport of amino acid has been studied in animals and man using the in vivo clearance method (Young and Freedman 1971). The slope of the reabsorption curve of lysine and arginine in the present normal subjects was nearly the same as that observed in animals (Wright et al 1947;Boorman 1971), showing a little wide splay and Tm that is often seen in other amino acid titration curves (Young and Freedman 1971). The renal transport mechanism of human kidney may be similar to that of animals.…”

Renal Handling of Diamino Acids in Lysinuric Protein Intolerance

“…This was 30-100% of the increase in arginine concentration, in molar units, in both patients with LPI and controls. The same effect has been observed in animals (23,24). Ornithine infusion influenced the plasma arginine concentration variably but to a lesser degree; the largest infusion used produced only a twofold increase in plasma arginine.…”

Performance and Concentration of Amino Acids in Plasma and Urine of Young Pigs Fed Diets with Excesses of Either Arginine or Lysine

“…These data indicate that arginine and(or) ornithine concentrations reached levels high enough to surpass efficient renal reabsorption of these amino acids in pigs fed the diet containing 2.8% total arginine. This also agrees well with the concept that arginine and(or) ornithine inhibit the renal reabsorption of lysine, citrulline, cystine and histidine (Beyer et al, 1947;Kamin and Handler, 1951;Weber et al, 1961;Boorman, 1971;Boorman and Falconer, 1972;Christensen and Cullen, 1973). Amino acids excreted in the urine represented a small and insignificant percentage of the amino acids consumed.…”

Renal transport of lysine and arginine in cystinuria.

“…Since Pitts (1943) first reported the titration curve of glycine in dog, renal transport of amino acid has been studied in animals and man using the in vivo clearance method (Young and Freedman 1971). The slope of the reabsorption curve of lysine and arginine in the present normal subjects was nearly the same as that observed in animals (Wright et al 1947;Boorman 1971), showing a little wide splay and Tm that is often seen in other amino acid titration curves (Young and Freedman 1971). The renal transport mechanism of human kidney may be similar to that of animals.…”

Renal Handling of Diamino Acids in Lysinuric Protein Intolerance

“…This was 30-100% of the increase in arginine concentration, in molar units, in both patients with LPI and controls. The same effect has been observed in animals (23,24). Ornithine infusion influenced the plasma arginine concentration variably but to a lesser degree; the largest infusion used produced only a twofold increase in plasma arginine.…”

Performance and Concentration of Amino Acids in Plasma and Urine of Young Pigs Fed Diets with Excesses of Either Arginine or Lysine

“…These data indicate that arginine and(or) ornithine concentrations reached levels high enough to surpass efficient renal reabsorption of these amino acids in pigs fed the diet containing 2.8% total arginine. This also agrees well with the concept that arginine and(or) ornithine inhibit the renal reabsorption of lysine, citrulline, cystine and histidine (Beyer et al, 1947;Kamin and Handler, 1951;Weber et al, 1961;Boorman, 1971;Boorman and Falconer, 1972;Christensen and Cullen, 1973). Amino acids excreted in the urine represented a small and insignificant percentage of the amino acids consumed.…”

Renal transport of lysine and arginine in cystinuria.

“…Since Pitts (1943) first reported the titration curve of glycine in dog, renal transport of amino acid has been studied in animals and man using the in vivo clearance method (Young and Freedman 1971). The slope of the reabsorption curve of lysine and arginine in the present normal subjects was nearly the same as that observed in animals (Wright et al 1947;Boorman 1971), showing a little wide splay and Tm that is often seen in other amino acid titration curves (Young and Freedman 1971). The renal transport mechanism of human kidney may be similar to that of animals.…”

Renal Handling of Diamino Acids in Lysinuric Protein Intolerance

“…This was 30-100% of the increase in arginine concentration, in molar units, in both patients with LPI and controls. The same effect has been observed in animals (23,24). Ornithine infusion influenced the plasma arginine concentration variably but to a lesser degree; the largest infusion used produced only a twofold increase in plasma arginine.…”